D-glucitol-[4,5-d2], a deuterium-labeled sugar alcohol known as isotopically labeled sorbitol, finds wide-ranging use in scientific and industrial realms. Here are the key applications of D-glucitol-[4,5-d2]:
Metabolic Tracing: Delving into metabolic studies, D-glucitol-[4,5-d2] plays a pivotal role in tracing and quantifying metabolic pathways. By integrating this isotopically labeled compound, researchers delve into the metabolic flux of sorbitol, unraveling its conversion to fructose. This method is indispensable for grasping the intricacies of carbohydrate metabolism dynamics and diagnosing complex metabolic disorders.
Pharmaceutical Research: In the realm of drug development, D-glucitol-[4,5-d2] emerges as a valuable tool for examining the pharmacokinetics of sorbitol-containing formulations. Utilizing this labeled compound, scientists scrutinize the absorption, distribution, metabolism, and excretion of drugs, vital information for optimizing drug formulations and securing their efficacy and safety.
Analytical Chemistry: Encompassing a critical role in mass spectrometry, D-glucitol-[4,5-d2] acts as an internal standard for precise quantitation needs. Its stable isotope composition enables the accurate measurement of sorbitol levels in biological samples, ensuring dependable analytical results crucial in clinical and research laboratory settings.
Food Science: Within the food industry landscape, D-glucitol-[4,5-d2] offers insights into the bioconversion of sorbitol within diverse food products. This isotopically labeled compound aids in tracking fermentation processes and decoding how microorganisms metabolize sorbitol. Such knowledge proves instrumental in enhancing food quality and spearheading the development of novel fermentation-based food products.
![D-glucitol-[4,5-d2]](https://resource.bocsci.com/structure/d-4-5-2h2-glucitol.gif)
