D-Fructose-[5-18O]

D-Fructose-[5-18O], a compound labeled with stable isotopes, holds significant value in biomedical and biochemical research. Here are the key applications of D-Fructose-[5-18O]:

Metabolic Pathway Tracing: Utilizing D-Fructose-[5-18O] in metabolic investigations allows researchers to trace the intricate flow of carbon atoms across various biochemical pathways. By introducing this labeled sugar, scientists can track the processing of fructose within cells and tissues, shedding light on convoluted metabolic networks and disease connections, such as those seen in diabetes and obesity.

Enzyme Mechanism Studies: In the realm of enzymology, D-Fructose-[5-18O] serves as a valuable tool for delving into the mechanisms of enzymes involved in fructose metabolism. By studying the interactions of enzymes with this labeled fructose, researchers can glean deep insights into catalytic processes and enzyme specificity. This exploration plays a pivotal role in formulating inhibitors or activators that can alter enzyme functions for therapeutic benefits.

Functional Imaging: Bridging the worlds of medical imaging and D-Fructose-[5-18O], researchers can leverage this labeled compound in conjunction with advanced techniques like Positron Emission Tomography (PET). By tagging tissues or organs with D-Fructose-[5-18O], real-time visualization of metabolic processes becomes achievable. This innovative approach is particularly valuable in diagnosing and monitoring metabolic irregularities and cancer progression.

Nutrition and Diet Studies: When applied in nutritional investigations, D-Fructose-[5-18O] offers insights into the absorption and utilization of fructose within the human body. By monitoring the journey of labeled fructose in dietary experiments, researchers can unravel the impact of different diets on metabolism. This knowledge is instrumental in guiding dietary recommendations and comprehending the role of fructose in the realm of health and disease.