D-glucitol-[6-13C,6,6'-d2]

D-glucitol-[6-13C,6,6'-d2], an isotopically labeled sugar alcohol, finds widespread utility in diverse research contexts. Here are the key applications of D-glucitol-[6-13C,6,6'-d2]:

Metabolic Flux Analysis: In the realm of metabolic flux analysis, D-glucitol-[6-13C,6,6'-d2] serves as a powerful tool for delineating carbon flow through intricate metabolic pathways. By scrutinizing how labeled carbon atoms are metabolized, researchers glean profound insights into cellular metabolism and energy generation. This knowledge plays a pivotal role in unraveling disease intricacies and fine-tuning metabolic engineering strategies for optimal efficiency.

NMR Spectroscopy: Delving into the realm of nuclear magnetic resonance (NMR) spectroscopy, this compound aids in exploring the structural dynamics and biomolecular interactions. The isotopic labeling amplifies signal resolution and sensitivity in NMR investigations, facilitating in-depth scrutiny of carbohydrate-protein interactions, conformational alterations, and other molecular phenomena. This sophisticated technique enables detailed analyses with unparalleled precision and depth.

Diabetic Research: A cornerstone of diabetic research, D-glucitol-[6-13C,6,6'-d2] emerges as a vital asset for delving into the metabolic intricacies of sorbitol—a sugar alcohol linked to diabetic complications. By monitoring the metabolic destiny of this labeled compound, researchers shed light on the role of sorbitol in conditions like diabetic neuropathy and cataracts. These investigations pave the way for developing therapeutic interventions to manage diabetes effectively.

Stable Isotope Labeling Studies: Within the domain of biochemical assays, D-glucitol-[6-13C,6,6'-d2] stands out for its significance in stable isotope labeling studies. By integrating this labeled compound into metabolic experiments, researchers gain unparalleled precision in tracking metabolic alterations and isotope distribution. This meticulous technique underpins quantitative analyses of metabolic pathways and fluxes within biological systems, offering invaluable insights for advancing biochemical research.