Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-012747 |
Molecular Formula: C6H12O5[18O] |
Molecular Weight: 182.16 |
Chemical Structure |
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Description | D-Fructose-[6-18O] is the labelled analogue of D-Fructose, which is a monosaccharide that naturally occurs in a large number of fruits and plants. |
Synonyms | D-[6-18O]fructose; D-fructose-6-18O; D-(-)-Fructose-6-18O; D-(-)-Levulose-6-18O; D-Arabino-2-hexulose-6-18O; Fructose-6-18O; Furucton-6-18O; Krystar-6-18O; Levulose-6-18O; Nevulose-6-18O |
IUPAC Name | (3S,4R,5R)-2-(hydroxymethyl)tetrahydro-2H-pyran-1-18O-2,3,4,5-tetraol |
Related CAS | 57-48-7 (unlabelled) |
Purity | ≥95%; >90% atom 18O |
Solubility | Soluble in Water (Sparingly) |
Appearance | Off-white Solid |
Storage | Store at -20°C |
D-Fructose-[6-18O], an isotopically labeled form of fructose, plays a crucial role in various biochemical and physiological studies. Here are the key applications of D-Fructose-[6-18O]:
Metabolic Flux Analysis: By leveraging D-Fructose-[6-18O], researchers can meticulously trace metabolic pathways in organisms. Incorporating this labeled fructose facilitates a detailed study of carbohydrate metabolism and the tracking of carbon atom flow through diverse metabolic routes. This in-depth analysis aids in unraveling disorders associated with metabolism and fine-tuning metabolic engineering strategies with precision.
NMR Spectroscopy: In the realm of nuclear magnetic resonance (NMR) spectroscopy, the use of D-Fructose-[6-18O] offers a unique window into the intricate details of carbohydrate structure and dynamics. The oxygen-18 isotope imparts distinct spectral characteristics, providing scientists with valuable insights into molecular conformations and interactions. This application is indispensable for advancing structural biology and the exploration of carbohydrate-based therapeutics with a nuanced approach.
Isotopic Labeling in Plant Studies: Within the domain of plant research, D-Fructose-[6-18O] serves as a valuable tool for delving into photosynthesis and other metabolic processes. By administering this labeled fructose to plants, researchers can observe how sugars are integrated and utilized during growth and development. This knowledge plays a pivotal role in enhancing crop yield and bolstering stress tolerance through the principles of metabolic engineering, offering innovative solutions for sustainable agriculture.
Nutritional Studies: In the realm of human and animal nutrition, D-Fructose-[6-18O] emerges as a significant asset for comprehending sugar metabolism and its impact on health. By monitoring the metabolism of this labeled fructose, scientists can delve into issues such as fructose malabsorption, insulin resistance, and obesity, shedding light on crucial aspects of metabolic health. These studies contribute immensely to the formulation of dietary recommendations and the design of tailored therapeutic interventions, shaping the landscape of nutritional science.
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