D-Lysine-[d8] Dihydrochloride - Isotope / BOC Sciences

General Information
Catalog: BLP-006064
Molecular Formula: C6H8D8Cl2N2O2
Molecular Weight: 227.15

General Information

Catalog: BLP-006064

Molecular Formula: C6H8D8Cl2N2O2

Molecular Weight: 227.15

Chemical Structure

Description	D-Lysine-3,3,4,4,5,5,6,6-d8 2HCl is a labelled D-Lysine 2HCl. Lysine is an essential amino acid obtained from red meats and fish. Lysine inhibits HSV growth via knocking out arginine.
Synonyms	D-Lysine-3,3,4,4,5,5,6,6-d8 Dihydrochloride
IUPAC Name	(2R)-2,6-diamino-3,3,4,4,5,5,6,6-octadeuteriohexanoic acid;dihydrochloride
Related CAS	790637-06-8 (free base) 10303-72-7 (unlabelled)
Canonical SMILES	C(CCN)CC(C(=O)O)N.Cl.Cl
InChI	InChI=1S/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/t5-;;/m1../s1/i1D2,2D2,3D2,4D2;;
InChI Key	JBBURJFZIMRPCZ-SDYKFIRESA-N
Purity	95% by CP; 98% atom D
Storage	Store at 2-8°C

D-Lysine-[d8] Dihydrochloride, a labeled amino acid, finds utility in a myriad of scientific and industrial contexts. Here are the key applications:

Protein Structure Studies: Integral to protein structure analysis, D-Lysine-[d8] Dihydrochloride is harnessed in conjunction with NMR spectroscopy to unravel the intricacies of protein folding, dynamics, and interactions. By integrating this isotopically enriched amino acid into proteins, researchers gain intricate insights into their structural behavior, shedding light on protein functionality and bolstering drug design endeavors.

Metabolic Research: The utilization of labeled D-Lysine-[d8] extends to tracking metabolic pathways within cellular and organismal systems. By scrutinizing the assimilation and turnover of D-Lysine-[d8], scientists delve into amino acid metabolism and protein synthesis rates, laying the groundwork for elucidating metabolic disorders and fine-tuning metabolic engineering strategies.

Pharmacokinetics: In the realm of pharmacokinetic exploration, D-Lysine-[d8] Dihydrochloride emerges as a fundamental tool for analyzing the fate of drugs within biological systems. Acting as a tracer, the labeled amino acid enables meticulous assessment of drug-protein interactions and the metabolic pathways traversed by therapeutic compounds. This data proves indispensable in the development of safe and efficacious pharmaceutical interventions.

Biomedical Research: Within the domain of biomedical inquiry, D-Lysine-[d8] Dihydrochloride serves as a linchpin in stable isotope labeling strategies for mass spectrometry-based proteomics studies. By integrating this labeled amino acid into cellular contexts, scientists quantify protein expression levels and discern post-translational modifications, unveiling potential biomarkers and unraveling the mechanisms underpinning various diseases.