Name: D-Lysine-[d4] Dihydrochloride
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-006065

Molecular Formula: C6H12D4Cl2N2O2

Molecular Weight: 223.14

Chemical Structure

Description	D-Lysine-4,4,5,5-d4 2HCl is a labelled D-Lysine 2HCl. Lysine is an essential amino acid obtained from red meats and fish. Lysine inhibits HSV growth via knocking out arginine.
Synonyms	D-Lysine-4,4,5,5-d4 Dihydrochloride; (R)-2,6-Diaminohexanoic Acid-d4 2HCl; H-D-Lys-OH-d4 2HCl
IUPAC Name	(2R)-2,6-diamino-4,4,5,5-tetradeuteriohexanoic acid;dihydrochloride
Related CAS	1202063-77-1 (free base) 10303-72-7 (unlabelled)
Canonical SMILES	C(CCN)CC(C(=O)O)N.Cl.Cl
InChI	InChI=1S/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/t5-;;/m1../s1/i1D2,2D2;;
InChI Key	JBBURJFZIMRPCZ-AYBNVTFNSA-N
Purity	95% by CP; 98% atom D
Storage	Store at 2-8°C

D-Lysine-[d4] Dihydrochloride is a stable isotope-labeled compound used in various biochemical and analytical applications. Here are some key applications of D-Lysine-[d4] Dihydrochloride:

Protein Structure and Function Studies: D-Lysine-[d4] Dihydrochloride is used in mass spectrometry-based proteomics to study protein structures and functions. By incorporating this labeled lysine into proteins, researchers can perform accurate quantification and identification of proteins and their post-translational modifications. This aids in understanding protein interactions and mechanisms in complex biological systems.

Metabolic Flux Analysis: In metabolic research, D-Lysine-[d4] Dihydrochloride is utilized to trace metabolic pathways and analyze metabolic fluxes. The stable isotope labeling allows scientists to monitor the incorporation and distribution of lysine in cellular metabolism. This information is crucial for studying metabolic disorders and engineering metabolic pathways in biotechnology.

Pharmacokinetic Studies: D-Lysine-[d4] Dihydrochloride is employed in pharmacokinetic studies to investigate the absorption, distribution, metabolism, and excretion (ADME) of therapeutic drugs. The labeled compound helps in tracking and quantifying lysine-containing drugs and their metabolites in biological samples. This application is essential for drug development and optimizing dosing regimens.

Protein Synthesis Research: D-Lysine-[d4] Dihydrochloride is used in studies of protein synthesis to understand ribosomal activity and translation efficiency. By incorporating the labeled lysine into newly synthesized proteins, researchers can measure protein synthesis rates and detect changes in response to various genetic and environmental factors. This contributes to the understanding of translational control mechanisms.