Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-008114 |
Molecular Formula: [13C]5H12O5 |
Molecular Weight: 157.11 |
Chemical Structure |
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Description | Isotope labelled analogue of D-arabinitol, a sugar alcohol. D-arabinitol was used as a diagnostic tool for the detection of fungal infections in neutropenic patients. |
Synonyms | D-[UL-13C5]arabinitol; D-arabinitol 13C5 |
IUPAC Name | (2R,4R)-pentane-1,2,3,4,5-pentaol-1,2,3,4,5-13C5 |
Related CAS | 488-82-4 (unlabelled) |
Melting Point | 99-101°C |
Purity | 98% by CP; 98% atom 13C |
Solubility | Soluble in DMSO, Methanol, Water |
Appearance | White Solid |
Storage | Store at -20°C |
D-arabinitol-[13C5], a stable isotope-labeled compound widely utilized in diverse bioscience applications, holds pivotal roles in various key applications. Here are some applications of D-arabinitol-[13C5]:
Metabolic Flux Analysis: By incorporating the isotopically labeled carbon atoms of D-arabinitol-[13C5] into metabolic intermediates, researchers can trace the metabolic pathways within biological systems. Monitoring the distribution of this labeled compound enables a real-time exploration of metabolic flux dynamics. This detailed analysis is essential for unraveling the intricate metabolic changes associated with diseases or metabolic engineering strategies.
Quantitative P+roteomics: Within quantitative proteomics, D-arabinitol-[13C5] serves as an internal standard for ensuring precise measurement of protein concentrations. Integrating the labeled compound into proteomic samples facilitates accurate quantification and comparison of protein levels. This technique is paramount for identifying differentially expressed proteins and deciphering their roles in diverse biological processes.
Research on Carbohydrate Metabolism: As a valuable tool in the study of carbohydrate metabolism across various organisms, D-arabinitol-[13C5] aids researchers in comprehending the roles and fates of sugar alcohols within different biological contexts. Its inclusion in metabolic studies provides insights into how specific enzymes interact with the labeled D-arabinitol, shedding light on enzyme kinetics and metabolic regulations.
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