Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013333 |
Molecular Formula: [13C]6H10O6 |
Molecular Weight: 184.09 |
Chemical Structure |
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Description | Labelled D-Glucosone. D-Glucosone is a key intermediate of a secondary metabolic pathway leading to the antibiotic cortalcerone. |
Synonyms | D-glucosone-U-13C6; D-[UL-13C6]arabino-hexosulose; D-2-ketoglucose-U-13C6 |
Related CAS | 1854-25-7 (unlabelled) |
D-glucosone-[UL-13C6], a universally labeled isotopic form of D-glucosone, plays a pivotal role in biochemical research. Explore its key applications:
Metabolic Tracing Studies: Utilizing D-glucosone-[UL-13C6] in metabolic tracing enables researchers to meticulously trace the intricate biochemical pathways of glucose metabolism. By integrating this labeled compound into metabolic investigations, scientists can monitor the intricate distribution and conversion of glucose-derived metabolites. This methodology sheds light on metabolic fluxes and unveils the metabolic alterations linked to diverse diseases.
Stable Isotope Labeling: D-glucosone-[UL-13C6] serves as an indispensable stable isotope label for high-precision mass spectrometry and nuclear magnetic resonance (NMR) analyses. This labeled compound facilitates the accurate quantification and identification of metabolites in complex biological samples. It proves particularly valuable in proteomics, lipidomics, and glycomics research, where precise measurement of metabolic changes is paramount for unraveling biological mysteries.
Glycation Research: Delve into the realm of glycation research with D-glucosone-[UL-13C6], a critical component in studying the glycation process implicated in advanced glycation end-product (AGE) formation within proteins. By leveraging this labeled sugar, researchers can dissect the kinetics and mechanisms of glycation reactions, providing insights into the roles of AGEs in aging and the pathogenesis of diabetes and other chronic ailments. Unravel the complexities of glycation processes with this essential tool.
Nutritional Biochemistry: In the domain of nutritional biochemistry, D-glucosone-[UL-13C6] serves as a key asset for investigating the metabolic destinies of dietary sugars and their impacts on health. Through monitoring the labeled glucose derivative, scientists can assess how dietary interventions shape glucose metabolism, offering crucial insights into developing nutritional strategies to address conditions like obesity, diabetes, and metabolic syndrome. Witness the intertwined relationship between diet and health with this informative tool at your disposal.
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