D-gulose-[UL-13C6]

D-gulose-[UL-13C6], a carbon-13 sugar uniformly labeled with multiple applications in scientific research. Here are the key applications of D-gulose-[UL-13C6]:

Metabolic Flux Analysis: Utilizing D-gulose-[UL-13C6] in metabolic flux analysis allows researchers to delve into carbohydrate metabolism within living organisms. By administering this isotopically labeled sugar to organisms, scientists can meticulously track its incorporation into diverse metabolic pathways. This approach sheds light on how cells harness sugars, offering profound insights into metabolic regulation.

NMR Spectroscopy: Widely employed in nuclear magnetic resonance (NMR) spectroscopy, this labeled sugar plays a pivotal role in exploring the structure and dynamics of carbohydrates. The uniform carbon-13 labeling facilitates detailed spectral analysis, simplifying the study of intricate molecular interactions. This application is paramount for unraveling the three-dimensional structures of biomolecules, pushing the boundaries of structural biology.

Isotope Labeling Studies: In isotope labeling studies, D-gulose-[UL-13C6] serves as a valuable tool for investigating the destiny of sugars in biochemical processes. By tracking the labeled carbon atoms, researchers can glean insights into enzymatic reactions and the flow of carbon skeletons through metabolic cycles. This methodology is particularly valuable for mapping metabolic pathways in both prokaryotic and eukaryotic cells, enabling a comprehensive understanding of cellular metabolism.

Nutritional Research: In the realm of nutrition science, D-gulose-[UL-13C6] is harnessed to explore the digestion and absorption of sugars within the human body. Administering this labeled sugar to study participants allows scientists to monitor its metabolic fate using mass spectrometry or NMR techniques. This approach furnishes crucial data on sugar metabolism and its implications for human health, contributing to advancements in nutritional research.