D-Glucitol-[UL-13C6,UL-d8]

D-Glucitol-[UL-13C6,UL-d8], a compound of sorbitol labeled with stable isotopes, finds extensive utility in diverse scientific research endeavors. Here are the multifaceted applications of D-Glucitol-[UL-13C6,UL-d8]:

Metabolic Flux Analysis: Within metabolic flux analysis, D-Glucitol-[UL-13C6,UL-d8] emerges as a pivotal tool for tracing and quantifying metabolic pathways within cellular systems. By meticulously tracking the labeled carbon and deuterium atoms across metabolic networks, researchers unearth invaluable insights into metabolite fluxes. This depth of understanding is paramount in unraveling the intricacies of cellular metabolism and refining industrial fermentation processes.

NMR Spectroscopy: The isotopically labeled D-Glucitol-[UL-13C6,UL-d8] shines as a premier probe for delving into nuclear magnetic resonance (NMR) spectroscopy studies. Scientists leverage its stable isotope labeling to probe the structure dynamics and interactions of biological molecules with unparalleled precision. This application elevates the resolution and sensitivity of NMR measurements, furnishing in-depth revelations of molecular mechanisms and dynamics.

Mass Spectrometry: Embarking on mass spectrometry-based investigations, D-Glucitol-[UL-13C6,UL-d8] plays a pivotal role in quantitatively analyzing metabolites. Its isotopic labeling capability empowers precise measurements of metabolic intermediates and end products, serving as a cornerstone in metabolic profiling, biomarker discovery, and pharmacokinetics studies. This cutting-edge technique stands as a linchpin in advancing our understanding of metabolic processes and disease mechanisms.

Biochemical Research: In the realm of biochemical research, D-Glucitol-[UL-13C6,UL-d8] assumes a crucial role as a reference standard for quantifying natural sorbitol. Its utility extends to studying enzymatic reactions involving sorbitol, particularly those catalyzed by aldose reductase. This foundational research aids in unraveling enzyme mechanisms, paving the way for the development of inhibitors aimed at mitigating diabetic complications and enhancing therapeutic interventions.