Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-012712 |
Molecular Formula: [13C]7H13NaO8.2H2O |
Molecular Weight: 291.13 |
Chemical Structure |
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Synonyms | alpha-D-[UL-13C7]glucoheptonic acid sodium salt dihydrate; D-glycero-D-[UL-13C7]guloheptonic acid; Sodium [UL-13C7]glucoheptonate dihydrate; α-D-[UL-13C7]glucoheptonic acid sodium salt dihydrate; D-Glycero-D-gulo-Heptonic Acid-13C7, Monosodium Salt, Dihydrate; D-α-Glucoheptonic Acid-13C7, Sodium Salt, Dihydrate; Sodium D-glycero-D-gulo-heptonate-13C7 Dihydrate; Sodium D-α-Glucoheptonate-13C7 Dihydrate |
IUPAC Name | sodium;(2R,3R,4S,5R,6R)-2,3,4,5,6,7-hexahydroxyheptanoate-13C7;dihydrate |
Related CAS | 10094-62-9 (unlabelled) 13007-85-7 (unlabelled anhydrous) 87-74-1 (unlabelled free base) |
Purity | ≥98%; ≥98% atom 13C |
Solubility | Soluble in Methanol (Very Slightly), Water (Slightly) |
Appearance | Off-white Solid |
Storage | Store at -20°C |
α-D-glucoheptonic acid-[UL-13C7] sodium salt dihydrate, a labeled compound serving various biochemical and analytical purposes, finds applications in diverse realms. Delve into the key applications:
Metabolic Flux Analysis: Dive into the intricate world of metabolic flux analysis, where this compound plays a pivotal role in tracing and quantifying glucose metabolism pathways within cells. By introducing a uniformly labeled carbon isotope, researchers unveil detailed metabolic processes using techniques like NMR or mass spectrometry. This exploration sheds light on metabolic network regulation and unveils potential metabolic bottlenecks that govern cellular activities.
Stable Isotope Labeling in Proteomics: Explore the realm of proteomics through the lens of stable isotope labeling with α-D-glucoheptonic acid-[UL-13C7] sodium salt dihydrate. This method enables precise quantification of protein abundances and facilitates the discrimination of protein isoforms, a boon in perplexing biological samples where distinguishing similar proteins poses a challenge. Unravel the complexities of protein expression dynamics with this advanced approach.
Glycosylation Studies: Embark on a journey into glycosylation pathways using the labeled compound as a guiding beacon in biosynthetic investigations. Witness how researchers track the incorporation of α-D-glucoheptonic acid into glycoproteins and glycoconjugates, unraveling the intricate roles of glycosylation in various physiological and pathological processes. Gain profound insights into the hidden world of sugar modifications shaping cellular functions.
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