DL-Glutamic acid-[3-13C]

DL-Glutamic acid-[3-13C], a stable isotope-labeled compound, is utilized in diverse scientific research applications. Here are the key applications:

Metabolic Flux Analysis: In the intricate realm of metabolic flux analysis, DL-Glutamic acid-[3-13C] is a crucial player, allowing researchers to intricately map out metabolic pathways and meticulously trace the flow of carbon atoms through cellular metabolism. By monitoring the labeled carbon atoms with precision, scientists can quantitatively evaluate the activity of specific metabolic pathways and unravel how cells adapt to varying conditions. This method provides invaluable insights into the sophisticated regulation of metabolism and unveils the underlying mechanisms of disease.

NMR Spectroscopy: Within the captivating domain of nuclear magnetic resonance (NMR) spectroscopy investigations, DL-Glutamic acid-[3-13C] serves as an indispensable asset for exploring the structure and dynamics of proteins, nucleic acids, and metabolites. The integration of [3-13C] into glutamic acid enhances spectral resolution and sensitivity, facilitating in-depth NMR explorations. By harnessing DL-Glutamic acid-[3-13C], researchers can decipher molecular interactions and conformational changes pivotal to biochemical processes, enriching our comprehension of intricate biological systems.

Drug Metabolism Studies: In the sphere of pharmacokinetics and drug metabolism research, DL-Glutamic acid-[3-13C] assumes a pivotal role in tracking the biotransformation of drugs within the body. Through labeling metabolic intermediates, scientists can meticulously monitor the journey of drugs and their metabolites, unearthing crucial insights into drug efficacy and safety. This application is indispensable for drug development endeavors and regulatory approvals, furnishing essential information to guarantee the efficacy and safety of pharmaceutical interventions.

Functional Imaging: Within the realm of medical imaging applications, DL-Glutamic acid-[3-13C] emerges as a versatile tracer for positron emission tomography (PET) and magnetic resonance imaging (MRI), facilitating the study of brain activity and other physiological processes. When integrated into metabolic pathways, the labeled compound enables real-time visualization of cellular activity and metabolic alterations. This cutting-edge application aids in the diagnosis and monitoring of neurological disorders and cancer, offering valuable insights into the dynamic processes unfolding within the human body.