Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009770 |
Molecular Formula: [13C]2C6N2S2O4H16 |
Molecular Weight: 270.34 |
Chemical Structure |
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Description | DL-Homocystine-[1,1'-13C2] is a labelelled DL-Homocystine, which is the double-bonded form of homocysteine. Increased level of homocysteine is associated with venous and arterial thrombosis. |
Synonyms | DL-Homocysteine dimer-1,1'-13C2 |
IUPAC Name | 2-amino-4-[(3-amino-3-hydroxycarbonylpropyl)disulfanyl](1-13C)butanoic acid |
Related CAS | 870-93-9 (unlabelled) |
Canonical SMILES | C(CSSCCC(C(=O)O)N)C(C(=O)O)N |
InChI | InChI=1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/i7+1,8+1 |
InChI Key | ZTVZLYBCZNMWCF-BFGUONQLSA-N |
Purity | 95% by HPLC; 99% atom 13C |
DL-Homocystine-[1,1'-13C2], a labeled analog of homocystine, is a powerful tool for research into metabolic pathways and enzyme kinetics. Here are key applications of DL-Homocystine-[1,1'-13C2] presented with high perplexity and burstiness:
Metabolic Tracing: Acting as a stable isotope tracer, DL-Homocystine-[1,1'-13C2] enables researchers to delve deep into metabolic studies. By integrating this labeled compound into experiments, scientists can meticulously trace the metabolic pathways and interactions of homocystine within biological systems. This application plays a crucial role in unraveling the significance of homocystine in sulfur amino acid metabolism and its implications in related diseases.
Enzyme Kinetics: In the realm of enzymology, DL-Homocystine-[1,1'-13C2] offers a sophisticated lens through which to explore enzyme mechanisms involving homocystine. Leveraging mass spectrometry, scientists can precisely quantify the labeled substrate and products, shedding light on enzyme activity and substrate specificity. This detailed approach is essential for uncovering inhibitors and modulators of metabolic enzymes, paving the way for advancements in enzymatic studies.
Nutritional Studies: DL-Homocystine-[1,1'-13C2] finds its place in nutritional research as a key player in investigating the impact of dietary intake on homocystine metabolism. Through analyzing the integration and metabolism of this labeled compound within organisms, researchers can evaluate the effects of various nutrients and interventions. This research aids in formulating dietary recommendations and interventions for conditions such as homocystinuria, providing valuable insights into personalized nutrition strategies.
Biochemical Pathway Elucidation: By employing DL-Homocystine-[1,1'-13C2] in biochemical assays, researchers can meticulously map out and validate the intricate pathways involved in homocystine metabolism. This approach unveils intermediates and pinpoints potential control points within the pathways, offering crucial information for targeting areas of therapeutic intervention. Such profound studies play a vital role in comprehensively understanding and addressing metabolic disorders, driving forward our knowledge of biochemical pathways.
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