DL-Lysine-[1-13C] Dihydrochloride

DL-Lysine-[1-13C] Dihydrochloride, a stable isotope-labeled amino acid, finds diverse applications in scientific research. Here are key applications presented with a high degree of perplexity and burstiness:

Metabolic Research: At the forefront of metabolic flux analysis, DL-Lysine-[1-13C] Dihydrochloride plays a pivotal role in elucidating the pathways and transformations of lysine within cellular metabolism. By integrating this labeled compound into metabolic investigations, researchers can meticulously monitor lysine utilization, offering profound insights into the intricate networks of metabolism. This application is particularly crucial for unraveling amino acid metabolic disorders and optimizing approaches in metabolic engineering.

Nutritional Studies: In the realm of nutritional science, DL-Lysine-[1-13C] Dihydrochloride is a cornerstone for investigating protein metabolism and lysine requirements across various organisms. Through assessing the incorporation of labeled lysine into bodily tissues, scientists can gauge the bioavailability of dietary lysine and the digestibility of proteins. This plays a vital role in crafting nutritionally balanced diets and enhancing strategies for animal and human nutrition.

Proteomics: Delving into the realm of quantitative proteomics, DL-Lysine-[1-13C] Dihydrochloride facilitates the determination of protein turnover rates and synthesis within cells. Utilizing mass spectrometry, researchers can differentiate between newly synthesized and pre-existing proteins by detecting the 13C label. This approach is instrumental in unraveling cellular proteostasis and the dynamics of proteins under diverse physiological and pathophysiological conditions.

Drug Development: In the domain of pharmacokinetics and drug development, DL-Lysine-[1-13C] Dihydrochloride serves as a crucial tracer for analyzing lysine-containing peptides and protein modifications. By tracking the distribution and metabolism of peptide-based drugs in vivo, scientists can optimize drug formulations and delivery systems, ensuring therapeutic efficacy and safety in drug development endeavors.