Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
General Information |
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Catalog: BLP-011533 |
CAS: 1142095-93-9 |
Molecular Formula: C20H11D4BrN6O |
Molecular Weight: 439.30 |
Chemical Structure |
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Catalog Number | Size | Price | Stock | Quantity |
---|---|---|---|---|
BLP-011533 | 1 mg | $159 | In stock | |
BLP-011533 | 5 mg | $734 | In stock |
Description | Etravirine-[d4] is the labelled analogue of Etravirine, which is a drug used for the treatment of HIV and a non-nucleoside reverse transcriptase inhibitor (NNRTI). |
Synonyms | Etravirine D4; 4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile-d4; Intelence-d4; R 165335-d4; TMC 125-d4 |
IUPAC Name | 4-[[4-amino-5-bromo-6-(4-cyano-2,6-dimethylphenoxy)pyrimidin-2-yl]amino]-2,3,5,6-tetradeuteriobenzonitrile |
Related CAS | 269055-15-4 (unlabelled) |
Canonical SMILES | CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N |
InChI | InChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27)/i3D,4D,5D,6D |
InChI Key | PYGWGZALEOIKDF-LNFUJOGGSA-N |
Purity | 98% |
Solubility | Soluble in DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
Appearance | Off-white Solid |
Application | The labeled form of Etravirine is an inhibitor of HIV reverse transcriptase and could be used in the treatment of HIV infection. |
Shelf Life | As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly |
Storage | Store at -20°C |
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