Name: Idebenone-[13C,d3]
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-005872

CAS: 1189907-75-2

Molecular Formula: C18[13C]H27D3O5

Molecular Weight: 342.45

Chemical Structure

Description	Idebenone-[13C,d3] is an isotope labelled compound of Idebenone. Idebenone is a short-chain benzoquinone drug.
Synonyms	2-(10-Hydroxydecyl)-6-methoxy-5-(methoxy-13C,d3)-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone-13C,d3; Avan-13C,d3; Daruma-13C,d3; Idebenone-13C,d3; Mnesis-13C,d3
IUPAC Name	2-(10-hydroxydecyl)-6-methoxy-3-methyl-5-(trideuterio(1-13C)methoxy)cyclohexa-2,5-diene-1,4-dione
Related CAS	58186-27-9 (unlabelled)
Canonical SMILES	CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO
InChI	InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3/i2+1D3
InChI Key	JGPMMRGNQUBGND-JVXUGDAPSA-N
Melting Point	48-50°C
Purity	98% by CP
Solubility	Slightly soluble in Chloroform, Methanol
Appearance	Orange Solid
Storage	Store at -20°C

Idebenone-[13C,d3] is a stable isotope-labeled form of idebenone used in scientific research for various applications. Here are some key applications of Idebenone-[13C,d3]:

Metabolic Research: Idebenone-[13C,d3] is utilized to study the metabolic pathways and pharmacokinetics of idebenone in biological systems. By tracking the labeled compound in metabolic studies, researchers can quantify its absorption, distribution, metabolism, and excretion. This information is crucial for understanding the drug's behavior and optimizing its use in therapeutic applications.

Neuroprotective Studies: Researchers employ Idebenone-[13C,d3] to investigate its neuroprotective properties in models of neurodegenerative diseases. By using the labeled compound, scientists can determine the mechanism of action of idebenone in preventing neuronal damage. This contributes to the development of potential treatments for conditions such as Alzheimer's disease and Friedreich's ataxia.

Oxidative Stress Research: Idebenone-[13C,d3] serves as a tool for studying oxidative stress-related cellular processes. By observing how the labeled molecule interacts with cellular components, researchers can assess its efficacy in reducing oxidative damage. This application helps in exploring idebenone's potential as an antioxidant therapy in various diseases.

Drug Interaction Studies: The labeled compound is used in drug interaction research to evaluate how idebenone might interact with other medications. By analyzing the metabolic profile of Idebenone-[13C,d3], scientists can predict potential drug-drug interactions in clinical scenarios.