Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013363 |
Molecular Formula: C5[13C]H14O6 |
Molecular Weight: 183.17 |
Chemical Structure |
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Description | Labelled L-glucitol. L-glucitol is a sugar alcohol obtained from the reduction of glucose and is naturally found in various fruits. |
Synonyms | L-[1-13C]glucitol; L-[1-13C]sorbitol; L-glucitol-1-13C |
IUPAC Name | (2S,3S,4S,5R)-(1-13C)hexane-1,2,3,4,5,6-hexol |
Related CAS | 6706-59-8 (unlabelled) |
Canonical SMILES | C(C(C(C(C(CO)O)O)O)O)O |
InChI | InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m0/s1/i1+1 |
InChI Key | FBPFZTCFMRRESA-RGICIRPASA-N |
L-glucitol-[1-13C], a labeled sugar alcohol, serves as a cornerstone in metabolic and biochemical research. Delve into the versatile applications of L-glucitol-[1-13C]:
Metabolic Tracing Studies: Unveiling the mysteries of cellular metabolism, L-glucitol-[1-13C] emerges as a pivotal tracer in metabolic pathway investigations. By integrating this labeled compound, researchers embark on a journey to trace metabolic flux and unravel the utilization pathways of sugar alcohols. This intricate process offers profound insights into energy metabolism and sheds light on the intricate web of specific metabolic routes.
NMR Spectroscopy: Embark on a captivating exploration of molecular dynamics with the aid of the 13C label within L-glucitol-[1-13C]. A beacon for nuclear magnetic resonance (NMR) spectroscopy, this compound facilitates in-depth investigations into molecular structure and dynamics. Witness the transformation of L-glucitol within diverse biochemical pathways as the utilization of labeled compounds elevates the sensitivity and specificity of NMR studies to new heights.
Glycosylation Studies: Transport yourself into the realm of glycosylation research, where L-glucitol-[1-13C] plays a transformative role in unraveling the synthesis and modification of glycoproteins and glycolipids. Through the incorporation of this labeled sugar alcohol into glycan structures, researchers unravel the intricacies of carbohydrate biosynthesis and assembly. This deep dive aids in decoding disorders linked to glycosylation and lays the foundation for innovative therapeutic interventions.
Microbial Fermentation: Embark on a voyage into microbial biotechnology where L-glucitol-[1-13C] emerges as a beacon for exploring microbial fermentation processes. Through the meticulous tracking of the labeled sugar alcohol, researchers delve into its transformation into a myriad of bio-products, including ethanol, lactic acid, and other valuable chemicals. Witness the optimization of microbial strains and fermentation conditions unfold, shaping the landscape of industrial applications with precision and innovation.
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