L-lyxose-[2-13C]

L-lyxose-[2-13C], a stable isotope-labeled sugar, is highly valued in diverse research fields. Here are applications of L-lyxose-[2-13C]:

Metabolic Pathway Tracing: Delving into cellular and microbial systems, scientists leverage L-lyxose-[2-13C] to meticulously trace metabolic pathways. By integrating this labeled sugar into metabolic processes, researchers carefully monitor its conversion into various metabolites using cutting-edge techniques like nuclear magnetic resonance (NMR) and mass spectrometry. This approach unravels intricate insights into metabolic fluxes and the dynamic interplay of pathways.

Structural Biology: Embracing multidimensional NMR spectroscopy, L-lyxose-[2-13C] becomes a vital tool in unraveling the structural nuances and dynamic behaviors of carbohydrates and glycoproteins. The 13C label affords a granular analysis of molecular interactions and conformations, crucial for deciphering the intricate structure-function relationships within biomolecules.

Enzyme Mechanism Studies: Pioneering enzyme studies, researchers employ L-lyxose-[2-13C] to probe deep into enzyme mechanisms, offering a labeled substrate that enables precise detection post-reaction. This innovative approach illuminates catalytic steps and enables the identification of intermediates in enzymatic reactions, pivotal for the development of enzyme inhibitors and the engineering of enzymes for diverse industrial applications.

Drug Metabolism: In the realm of pharmaceutical exploration, L-lyxose-[2-13C] emerges as a cornerstone for investigating drug metabolism and pharmacokinetics. By integrating this labeled sugar into drug compounds, scientists meticulously monitor the distribution, metabolism, and elimination of the drug within living organisms. This comprehensive understanding of the drug’s metabolic destiny aids in optimizing its medicinal properties and shaping its pharmacological efficacy.