L-2-Aminobutyric Acid-[d6]

L-2-Aminobutyric Acid-[d6], a deuterium-labeled compound, has diverse applications in various bioscience domains. Here are the key applications of L-2-Aminobutyric Acid-[d6]:

Metabolomics: Utilized as an internal standard in mass spectrometry-based metabolomic investigations, L-2-Aminobutyric Acid-[d6] plays a pivotal role. By juxtaposing the abundance of this labeled compound against endogenous metabolites, researchers can achieve precise quantification of metabolites in intricate biological samples. This method aids in pinpointing metabolic shifts linked to diseases or physiological fluctuations, shedding light on the intricate metabolic web within organisms.

Drug Metabolism Studies: In the realm of pharmacokinetic analyses, L-2-Aminobutyric Acid-[d6] emerges as a cornerstone for probing the destiny of drugs post-administration. Its deuterium labeling enables clear differentiation between the administered drug and its metabolic byproducts. This dissection is instrumental in unraveling the absorption, distribution, metabolism, and excretion (ADME) pathways of drugs, providing critical insights that underpin effective drug development strategies.

Isotope Dilution Analysis: In the realm of analytical chemistry, L-2-Aminobutyric Acid-[d6] stands as a beacon, guiding researchers through isotope dilution methodologies. Acting as a reference standard, this compound in its labeled form facilitates precise quantification of analytes when co-administered with their natural counterparts. This meticulous technique finds particular utility in trace analysis and the quantification of bioactive compounds, enriching research and clinical endeavors with meticulous measurements and insights.

Protein Synthesis Studies: Operating at the crossroads of in vitro and in vivo protein synthesis, L-2-Aminobutyric Acid-[d6] emerges as a key player in unraveling the intricacies of protein dynamics. By integrating this labeled amino acid into proteins during synthesis, researchers gain a unique vantage point to trace and scrutinize protein behavior. Delving into newly synthesized proteins, scientists can uncover nuances of protein turnover, post-translational modifications, and metabolic labeling across diverse biological systems, unveiling the dance of biomolecules within living organisms.