L-Ascorbic Acid-[5-13C]

L-Ascorbic Acid-[5-13C], an isotopically labeled variant of vitamin C, finds primary usage in research endeavors. Here are the crucial applications of L-Ascorbic Acid-[5-13C]:

Metabolic Tracing: Embedded in metabolic research, L-Ascorbic Acid-[5-13C] serves as a beacon for tracing the assimilation and metamorphosis of vitamin C across diverse biochemical pathways. By scrutinizing the carbon labels, researchers can chart the ebbs and flows of ascorbate metabolism within cellular and tissue specimens. This method sheds light on the intricate involvement of vitamin C in cellular processes and disease pathologies.

Nutritional Research: In the realm of nutritional sciences, L-Ascorbic Acid-[5-13C] acts as a window into the bioavailability and absorption nuances of vitamin C sourced from different dietary outlets. By monitoring the labeled compound in human or animal trials, scientists can gauge the efficiency of vitamin C absorption and utilization within the body. This knowledge forms the bedrock for crafting efficacious dietary guidelines and supplements.

Pharmacokinetics: Vital for pharmacokinetic assessments, L-Ascorbic Acid-[5-13C] stands as a linchpin for exploring the distribution, metabolism, and elimination patterns of vitamin C post-administration. Researchers track the concentration of the labeled vitamin in blood, urine, and tissues across temporal bounds. Such investigations are pivotal for delineating the optimal dosing regimens and therapeutic potentials of vitamin C in clinical milieus.

Oxidative Stress Research: Facilitating studies on the antioxidant prowess of vitamin C and its combat against oxidative stress, L-Ascorbic Acid-[5-13C] plays a pivotal role. Scientists leverage the labeled compound to quantify the uptake and utilization of ascorbate in response to oxidative challenges in cellular and animal models. This application unravels the defensive mechanisms of vitamin C against oxidative harm, unveiling its therapeutic merits in shielding against cellular damage.