L-Arginine-[15N4] hydrochloride is an isotopically labeled compound that is widely used in various scientific research applications. Here are some key applications of L-Arginine-[15N4] hydrochloride:
Metabolic Tracing: L-Arginine-[15N4] hydrochloride is used in metabolic tracing studies to track the incorporation of nitrogen into metabolic pathways. By utilizing this isotopically labeled compound, researchers can gain insights into nitrogen metabolism and the synthesis of important biomolecules. This is particularly beneficial for studying amino acid turnover and protein synthesis rates in different biological systems.
Proteomics Research: In proteomics, L-Arginine-[15N4] hydrochloride serves as an essential tool for quantitative mass spectrometry-based techniques. It allows for the precise quantification of proteins by enabling the measurement of isotopic enrichment in peptide fragments. This application is crucial for comparative proteomics studies where researchers aim to understand protein expression differences across various biological conditions.
Nutritional Studies: L-Arginine-[15N4] hydrochloride is employed in nutritional research to investigate arginine metabolism and its effects on health. By administering this isotopically labeled amino acid to study subjects, researchers can assess its absorption, utilization, and conversion in the body. This information helps in understanding the role of arginine in various physiological processes, including immune function and cardiovascular health.
Pharmacokinetics and Drug Metabolism: In the field of pharmacokinetics, L-Arginine-[15N4] hydrochloride is used to assess drug metabolism and disposition. The compound acts as a probe for evaluating how drugs are metabolized and eliminated in different organisms. Its use in this context aids in optimizing drug dosing regimens and understanding individual variability in drug response.
![L-Arginine-[15N4] hydrochloride](https://resource.bocsci.com/structure/204633-95-4.gif)
