L-Arginine-[guanido-13C] hydrochloride

L-Arginine-[guanido-13C] hydrochloride, a stable isotope-labeled compound, finds diverse applications in scientific and medical fields. Delve into the high perplexity and burstiness of its key applications:

Metabolic Research: Widely embraced in metabolic inquiries, L-Arginine-[guanido-13C] hydrochloride serves as a cornerstone in tracing and quantifying arginine metabolism within cellular and organismal landscapes. By integrating this tracer into metabolic highways, researchers unearth insights into arginine's pivotal roles in nitric oxide genesis and protein synthesis. This potent compound furnishes precise data on fluxes and kinetics, unraveling metabolic perturbations in ailments like cardiovascular maladies and cancer.

Pharmacokinetics Studies: Offering a window into the pharmacokinetics domain, this labeled entity empowers scientists to scrutinize the journey of arginine supplements or arginine-laden medications. Harnessing its stable isotope imprint, researchers trail the absorption, distribution, metabolism, and excretion pathways of arginine within the body's confines. These studies orchestrate the optimal crafting of dosing schedules and evaluate the bioaccessibility of arginine-infused therapeutics.

Clinical Nutrition: In the realm of clinical endeavor, L-Arginine-[guanido-13C] hydrochloride takes center stage in evaluating arginine requisites and utilization across diverse populations encompassing athletes and cohorts with distinct nutritional demands. By dissecting its metabolic destiny, scientists sculpt tailored dietary directives and supplementation blueprints. This facet contributes to a nuanced comprehension of nutritional maneuvers aimed at fueling performance peaks and bolstering recuperative endeavors.

Proteomics Research: Branching into the nucleus of proteomics, L-Arginine-[guanido-13C] hydrochloride emerges as a linchpin in stable isotope labeling by amino acids in cell culture (SILAC) undertakings. This labeling stratagem propels the quantification of protein expression levels and turnover rates within intricate biological reservoirs. Researchers decode variations in protein arrays under sundry contexts, unveiling potential biomarkers and therapeutic crosshairs amidst the shifting protein landscapes.