Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-013213 |
CAS: 149153-08-2 |
Molecular Formula: C5[13C]H8O6 |
Molecular Weight: 177.11 |
Chemical Structure |
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Description | L-Ascorbic Acid-[6-13C] is the labelled analogue of Vitamin C. Vitamin C is a naturally occurring organic compound with antioxidant properties. |
Synonyms | Vitamin C-6-13C |
IUPAC Name | (2R)-2-[(1S)-1,2-dihydroxy(2-13C)ethyl]-3,4-dihydroxy-2H-furan-5-one |
Related CAS | 50-81-7 (unlabelled) |
Canonical SMILES | C(C(C1C(=C(C(=O)O1)O)O)O)O |
InChI | InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1/i1+1 |
InChI Key | CIWBSHSKHKDKBQ-GAEYKTCYSA-N |
L-Ascorbic Acid-[6-13C], a stable isotopically labeled variation of Vitamin C, serves as a valuable tool in metabolic studies and diverse research endeavors. Explore below its key applications:
Metabolic Tracing: Delving into metabolic tracing, L-Ascorbic Acid-[6-13C] plays a pivotal role in unraveling the intricate biosynthesis and degradation pathways of Vitamin C within biological systems. By meticulously tracking the labeled compound, researchers gain insights into metabolic fluxes and partitioning dynamics within cells and tissues, shedding light on vitamin absorption, utilization, and overall metabolism intricacies.
Nutritional Studies: In the realm of nutritional research, L-Ascorbic Acid-[6-13C] serves as a guiding beacon, aiding scientists in deciphering the complex dynamics of Vitamin C within the human body, including its bioavailability and kinetics. Through ingestion of the labeled vitamin, participants offer valuable insights through subsequent blood, urine, or tissue samples, unveiling the processing mechanisms of Vitamin C. These revelations contribute significantly to shaping dietary intake recommendations and supplementation strategies.
Biochemical Research: At the core of biochemical investigations, L-Ascorbic Acid-[6-13C] takes center stage, offering a window into its roles as an antioxidant and enzyme cofactor. By scrutinizing the labeled vitamin's participation in diverse biochemical reactions, researchers unlock the intricate mechanisms behind its functions in mitigating oxidative stress and supporting enzymatic activities. These profound insights are pivotal in comprehending the health benefits and mechanisms of action underpinning Vitamin C.
Pharmacokinetics: In the realm of pharmacokinetic explorations, L-Ascorbic Acid-[6-13C] plays a crucial role in scrutinizing the absorption, distribution, metabolism, and excretion pathways of Vitamin C within the body. Through precise administration of the isotopically labeled compound and subsequent analysis of biological samples, researchers craft detailed pharmacokinetic profiles, enabling the optimization of therapeutic dosing regimens. This essential information lays the foundation for the development of effective Vitamin C supplements and therapeutic formulations, driving advancements in pharmacological interventions.
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