L-Asparagine-[13C4,15N2]

L-Asparagine-[13C4,15N2], a labeled compound utilized in research to explore metabolic pathways, protein synthesis, and cellular processes, serves as a cornerstone for various scientific investigations. Here are key applications of L-Asparagine-[13C4,15N2] presented with a high degree of perplexity and burstiness:

Metabolic Tracing: Infused with carbon-13 and nitrogen-15 isotopes, L-Asparagine-[13C4,15N2] acts as a critical tracer in metabolic investigations, charting the journey and transformations of asparagine across diverse pathways. Researchers harness this tool to quantify shifts in amino acid metabolism and elucidate the energy-producing role of asparagine. This technique proves indispensable in scrutinizing diseases characterized by metabolic irregularities, such as cancer.

Protein Synthesis Studies: Within the realm of proteomics, L-Asparagine-[13C4,15N2] emerges as a pivotal agent for deciphering the pace and magnitude of protein synthesis within cellular domains. By integrating labeled asparagine into freshly minted proteins, scientists conduct mass spectrometry analyses to probe protein turnover and synthesis efficacy. This application unveils nuanced insights into cellular protein dynamics and regulatory mechanisms under varying circumstances.

Nutritional Research: Serving as a beacon in the domain of nutritional science, this compound illuminates the assimilation and metabolic fate of asparagine across divergent dietary scenarios. Through scrutinizing the destiny of labeled asparagine within the body, researchers evaluate the nutritional worth and metabolic implications of meals rich in asparagine. This endeavor aids in crafting tailored dietary guidelines and grasping amino acid requisites.

Tumor Metabolism Research: In the realm of cancer inquiry, L-Asparagine-[13C4,15N2] emerges as a potent ally, shedding light on how tumor cells remodel asparagine metabolism to bolster their proliferation and persistence. Armed with this isotope-laden amino acid, researchers delve into critical metabolic pathways that sustain tumor expansion. Discoveries gleaned from these endeavors pave the way for targeted therapies that disrupt nutrient streams to cancerous cells, charting new avenues in cancer treatment strategy.