Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009815 |
CAS: 136743-62-9 |
Molecular Formula: C4[13C]2H12N2O4S2 |
Molecular Weight: 242.29 |
Chemical Structure |
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Description | L-Cystine-[1,1'-13C2] is a labelled L-Cystine. Cystine is a dimeric non-essential amino acid formed from cysteine. Cystine acts as an antioxidant and protects tissues from radiation and pollution. |
IUPAC Name | (2R)-2-amino-3-[[(2R)-2-amino-2-hydroxycarbonylethyl]disulfanyl](1-13C)propanoic acid |
Related CAS | 56-89-3 (unlabelled) |
Isomeric SMILES | C([C@@H]([13C](=O)O)N)SSC[C@@H]([13C](=O)O)N |
Canonical SMILES | C(C(C(=O)O)N)SSCC(C(=O)O)N |
InChI | InChI=1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1/i5+1,6+1 |
InChI Key | LEVWYRKDKASIDU-RDMIOTRCSA-N |
Melting Point | 240°C |
Purity | 98% by HPLC; 99% atom 13C |
L-Cystine-[1,1'-13C2], a stable isotope-labeled compound widely utilized in scientific research, boasts diverse applications across multiple fields, including metabolic studies, protein synthesis, and beyond. Here are key applications of L-Cystine-[1,1'-13C2], presented with a high degree of perplexity and burstiness:
Metabolic Tracing: Immersed in the realm of metabolic studies, L-Cystine-[1,1'-13C2] emerges as a crucial tool for tracing the intricate pathways of cystine and cysteine metabolism within organisms. By seamlessly integrating the labeled compound into biological systems, researchers can meticulously track the flow and transformation of sulfur amino acids. This methodology proves particularly invaluable in unraveling disorders associated with sulfur metabolism and devising targeted interventions to effectively modulate metabolic pathways.
Protein Structure and Function Analysis: At the forefront of protein biochemistry, L-Cystine-[1,1'-13C2] assumes a pivotal role as a key component for scrutinizing disulfide bond formation and protein folding dynamics. Harnessing this isotopically labeled cystine, scientists can delve into the structural intricacies and stability of proteins, illuminating their functionality. The insights gleaned from these investigations play a critical role in shaping therapeutic proteins and unraveling the complexities of diseases characterized by abnormal protein folding.
Nutritional Studies: Within the domain of nutritional research, L-Cystine-[1,1'-13C2] plays a crucial role in dissecting the contributions of cystine to diet and assimilation processes. Through the strategic incorporation of isotopically labeled cystine into dietary inquiries, researchers can discern the bioavailability and metabolic destiny of cystine across various dietary scenarios. These revelations not only inform dietary guidelines but also influence the development of targeted nutritional supplements tailored to optimize cystine assimilation.
NMR and Mass Spectrometry: Serving as a versatile probe in nuclear magnetic resonance (NMR) and mass spectrometry analyses, L-Cystine-[1,1'-13C2] enhances the sensitivity and resolution of these cutting-edge techniques, enabling a nuanced examination of complex biological mixtures. This strategic utilization of isotopic labeling facilitates the meticulous scrutiny of biomolecular interactions and the elucidation of intricate metabolic pathways. By leveraging this approach, researchers can unveil the veiled complexities of biological processes, paving the path for groundbreaking discoveries in the realm of biochemistry.
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