Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009019 |
Molecular Formula: C5H10ClN[17O]4 |
Molecular Weight: 187.6 |
Chemical Structure |
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Description | L-Glutamic acid-[17O4] hydrochloride is an isotope labelled derivative of L-Glutamic acid, a non-essential amino acid. Glutamic acid is a non-essential amino acid that acts as an excitatory neurotransmitter in the CNS. |
Synonyms | L-Glutamic acid hydrochloride-17O4 |
IUPAC Name | L-glutamic-17O4 acid;hydrochloride |
Related CAS | 138-15-8 (unlabelled) |
Purity | 98% by CP; 30% atom 17O |
Storage | Store at 2-8°C |
L-Glutamic acid-[17O4] hydrochloride, an isotopically labeled compound, finds diverse applications in both research and industry. Explore its versatile uses through high perplexity and burstiness:
Stable Isotope Tracing: Embraced in metabolic studies, L-Glutamic acid-[17O4] hydrochloride is a cornerstone for tracing metabolic pathways. By integrating this stable isotope-labeled compound into cellular metabolism, researchers can meticulously follow and quantify the flow of glutamic acid across diverse biochemical pathways. This cutting-edge technique unveils intricate insights into metabolic fluxes and pathway dynamics, unraveling the complexities of cellular processes.
Mass Spectrometry: Within the realm of mass spectrometry-based proteomics and metabolomics, L-Glutamic acid-[17O4] hydrochloride stands out as a crucial internal standard. Its distinctive isotopic signature enables precise quantification of glutamic acid within intricate biological samples, elevating the accuracy and dependability of analytical measurements. This precision fosters robust data interpretation, empowering researchers to extract meaningful insights from complex data sets.
Neuroscience Research: Delving into neuroscience studies, L-Glutamic acid-[17O4] hydrochloride emerges as a key player in investigating neurotransmitter dynamics and synaptic activity. As a pivotal excitatory neurotransmitter in the brain, glutamic acid's labeled form aids in exploring its pivotal role in synaptic transmission and neurochemical cycles. By shedding light on disorders linked to glutamate dysregulation, such as epilepsy and neurodegenerative diseases, this research contributes to deepening our understanding of complex brain functions.
Enzyme Kinetics: In the realm of enzymology, L-Glutamic acid-[17O4] hydrochloride serves as a valuable tool for studying enzyme-catalyzed reactions involving glutamate. Leveraging the isotopically labeled substrate, researchers can meticulously track reaction rates and mechanisms with enhanced precision. This critical information plays a pivotal role in enzyme engineering and the advancement of enzyme-based therapies and diagnostics, paving the way for innovative breakthroughs in the field.
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