L-Glutamic acid-[2-13C]

L-Glutamic acid-[2-13C], a stable isotope-labeled compound, finds extensive use in diverse scientific endeavors. Here are the key applications of L-Glutamic acid-[2-13C]:

Metabolic Flux Analysis: Serving as a vital component in metabolic flux analysis, L-Glutamic acid-[2-13C] acts as a tracer to explore the intricate pathways and dynamic nature of metabolism within living cells. By monitoring the incorporation of the 13C label, researchers can map the flow of carbon through diverse biochemical avenues, shedding light on cellular metabolism and pinpointing crucial metabolic bottlenecks.

NMR Spectroscopy: With its 13C label, L-Glutamic acid-[2-13C] emerges as a prized probe in nuclear magnetic resonance (NMR) spectroscopy investigations. Scientists utilize this compound to delve into protein-ligand interactions, protein folding, and other applications in structural biochemistry. The precise labeling yields high-resolution data, crucial for unraveling molecular structures and dynamics with precision.

Glutamate Receptor Studies: Delving into the realm of neurotransmission and neurological disorders, L-Glutamic acid-[2-13C] serves as a cornerstone in the study of glutamate receptors. These receptors play pivotal roles in signaling pathways and are implicated in various neurological conditions. By observing how the labeled glutamate interacts with these receptors, scientists garner insights into receptor functionality, signaling mechanisms, and potential avenues for therapeutic intervention, guiding the development of treatments for conditions like epilepsy and neurodegenerative diseases.

Environmental Tracing: Stepping into the domain of environmental sciences, L-Glutamic acid-[2-13C] emerges as a key player in tracing the destiny and movement of organic compounds within ecosystems. By tracking the 13C label, researchers delve into microbial degradation processes and nutrient cycling in soil and water environments. This knowledge is pivotal for unraveling ecological dynamics, paving the way for strategic decisions in environmental conservation and remediation efforts.