L-Glutamine-[1,2-13C2]

L-Glutamine-[1,2-13C2], a stable isotope-labeled amino acid, plays a pivotal role in metabolic research and biochemical studies. Here are the key applications of L-Glutamine-[1,2-13C2]

Metabolic Flux Analysis: Utilizing L-Glutamine-[1,2-13C2], researchers delve into tracing carbon flow within metabolic pathways, enabling the intricate analysis of metabolic fluxes in cellular systems. By integrating this labeled amino acid into cells, scientists gain insights into the metabolic fate of glutamine and its contributions to diverse biosynthetic processes. This critical approach enhances our comprehension of cellular metabolism, shedding light on potential metabolic dysregulations implicated in diseases like cancer

Isotope Ratio Mass Spectrometry: In the realm of biochemical research, L-Glutamine-[1,2-13C2] is paired with isotope ratio mass spectrometry (IRMS) to quantitatively assess biochemical reactions involving glutamine. This precision technique empowers researchers to delve deep into enzyme kinetics and metabolic pathways, unraveling dynamic changes within metabolic networks. These insights drive the development of innovative therapeutic strategies, harnessing the power of isotopic analysis to navigate the complex metabolic landscape

NMR Spectroscopy: Within the domain of nuclear magnetic resonance (NMR) spectroscopy, L-Glutamine-[1,2-13C2] serves as a valuable tool for exploring the structure and dynamics of glutamine and its derivatives in biological systems. By leveraging labeled isotopes, researchers enhance the sensitivity and resolution of NMR signals, facilitating detailed structural elucidation. This application proves particularly advantageous in dissecting the interactions of glutamine with biomolecules and in mapping intricate metabolic pathways, offering a deeper understanding of biological processes at a molecular level

Labeling Studies in Plant Biology: In the context of plant biological investigations, L-Glutamine-[1,2-13C2] emerges as a key player in unraveling nitrogen metabolism and amino acid biosynthesis. By monitoring the assimilation of labeled glutamine in plants, researchers explore the utilization of nitrogen in diverse biosynthetic processes, illuminating nutrient allocation dynamics within plant systems. This knowledge informs agricultural practices aimed at enhancing crop yield and nutrient content, underscoring the pivotal role of isotopic labeling in advancing sustainable agricultural solutions