Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-004333 |
CAS: 90147-15-2 |
Molecular Formula: C5[13C]H14N2O2.HCl |
Molecular Weight: 183.64 |
Chemical Structure |
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Description | L-Lysine-[13C] Hydrochloride is the labelled analogue of L-Lysine hydrochloride. L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. |
Synonyms | L-Lysine-1-13C hydrochloride; L-Lysine-13C HCl; (S)-2,6-Diaminohexanoic acid 13C, monohydrochloride; L-Lysine-13C monohydrochloride |
IUPAC Name | (2S)-2,6-diamino(1-13C)hexanoic acid;hydrochloride |
Related CAS | 657-27-2 (unlabelled) |
Canonical SMILES | C(CCN)CC(C(=O)O)N.Cl |
InChI | InChI=1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1/i6+1; |
InChI Key | BVHLGVCQOALMSV-SKBIKIRISA-N |
Melting Point | 263-264°C (dec.) (lit.) |
Purity | 95% by HPLC; 99% atom 13C |
L-Lysine-[1-13C] hydrochloride, a stable isotope-labeled amino acid renowned for its diverse applications in research and industry, shines in various realms. Here are key applications of L-Lysine-[1-13C] hydrochloride depicted with high perplexity and burstiness:
Metabolic Tracing: Delving into metabolic intricacies, scientists employ L-Lysine-[1-13C] hydrochloride as a potent tracer to unravel the mysteries of amino acid metabolism and protein turnover. By integrating this labeled amino acid into metabolic pathways, researchers embark on a journey to trace lysine's journey and scrutinize its integration into proteins. This endeavor yields invaluable insights into the intricate dance of metabolism and nutrient utilization across diverse biological systems.
Protein Synthesis Studies: Unveiling the secrets of protein biosynthesis, L-Lysine-[1-13C] hydrochloride takes center stage in research endeavors. Integrated into cell cultures or organisms, this compound becomes a cornerstone for analyzing protein synthesis rates, shedding light on the dynamic world of protein production. This application proves particularly indispensable in exploring protein dynamics, gene expression nuances, and translational control mechanisms, elevating our understanding of cellular machinations.
NMR Spectroscopy: Draped in the cloak of nuclear magnetic resonance (NMR) spectroscopy, L-Lysine-[1-13C] hydrochloride emerges as a beacon for probing the structural intricacies and dynamic nature of proteins and other macromolecules. The 13C label casts a unique NMR signal spotlight on lysine residues within proteins, unveiling structural conformations and intricate protein-ligand interactions at an atomic scale. This application heralds a new era in unraveling the mysteries of molecular architecture with unparalleled precision.
Nutrition and Dietary Studies: In the realm of nutritional science, L-Lysine-[1-13C] hydrochloride stands tall as a cornerstone for examining lysine bioavailability and metabolism within dietary landscapes. By infusing this labeled compound into dietary formulations, researchers embark on a journey to untangle the digestive, absorptive, and utilization pathways of lysine within the human body. These studies serve as beacons in illuminating essential amino acid requirements and fine-tuning nutritional interventions for optimal health outcomes.
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