Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009932 |
CAS: 1314753-85-9 |
Molecular Formula: C16H26D4N2O6 |
Molecular Weight: 350.45 |
Chemical Structure |
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Description | L-Lysine-[4,4,5,5-d4]-bis-N-t-BOC is a labelled L-Lysine-bis-N-t-BOC. Lysine is an essential amino acid obtained from red meats and fish. Lysine inhibits HSV growth via knocking out arginine. |
Synonyms | BOC-L-Lys-BOC-OH-d4 |
Related CAS | 2483-46-7 (unlabelled) |
Purity | 95% by HPLC; 98% atom D |
L-Lysine-[4,4,5,5-d4]-bis-N-t-BOC, a deuterated lysine derivative, finds widespread use in various research and industrial settings. Here are the key applications:
Proteomics Research: In the intricate realm of proteomics, L-Lysine-[4,4,5,5-d4]-bis-N-t-BOC plays a pivotal role in stable isotope labeling for mass spectrometry. By harnessing deuterium labeling, researchers unlock the power to quantitatively analyze protein expression levels within complex biological samples. This analytical prowess aids in unraveling the mysteries of protein function, interactions, and modifications across diverse biological milieus.
Drug Metabolism Studies: Delving into drug metabolism, this compound serves as a beacon for researchers probing how pharmaceutical entities undergo metabolic transformations within the body. Through the integration of deuterium-labeled lysine derivatives, scientists embark on a journey to trace intricate metabolic pathways and elucidate the pharmacokinetics of medicinal compounds. This knowledge forms the bedrock for refining drug formulations and shaping optimal dosing strategies, heralding a new era of precision medicine.
Chemical Synthesis: Embarking on the frontier of organic synthesis, L-Lysine-[4,4,5,5-d4]-bis-N-t-BOC emerges as a cornerstone for crafting intricate molecules. Infused with deuterium atoms, this compound exerts a profound influence on reaction mechanisms and product stability, guiding the synthesis of labeled peptides, protein analogs, and other bioactive compounds. Its utility transcends mere chemical reactions, offering a gateway to unlock the secrets of molecular complexity.
Biomedical Research: Navigating the labyrinth of biomedical inquiry, deuterated compounds like L-Lysine-[4,4,5,5-d4]-bis-N-t-BOC illuminate the path to understanding protein turnover and degradation. By monitoring the assimilation and breakdown of deuterium-labeled amino acids, researchers gain intimate insights into the dynamic dance of proteins within cellular realms. This nuanced exploration holds the key to unraveling the complexities of protein-related diseases, such as neurodegenerative disorders, shedding light on the intricate interplay between cellular processes and pathological states.
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