Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009740 |
Molecular Formula: C5[13C]H14N[15N]O2.HCl |
Molecular Weight: 184.63 |
Chemical Structure |
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Description | L-Lysine-[6-13C,ε-15N] hydrochloride is a labelled L-Lysine HCl. Lysine is an essential amino acid obtained from red meats and fish. Lysine inhibits HSV growth via knocking out arginine. |
Synonyms | L-Lysine-6-13C,epsilon-15N hydrochloride |
IUPAC Name | (2S)-2-amino-6-(15N)azanyl(6-13C)hexanoic acid;hydrochloride |
Related CAS | 657-27-2 (unlabelled) |
Canonical SMILES | C(CCN)CC(C(=O)O)N.Cl |
InChI | InChI=1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1/i4+1,7+1; |
InChI Key | BVHLGVCQOALMSV-XYHPNNNYSA-N |
Melting Point | 263-264°C (dec.) (lit.) |
Purity | 98% by HPLC; 98% atom 15N, 99% atom 13C |
L-Lysine-[6-13C,ε-15N] hydrochloride, an isotopically labeled amino acid employed in diverse scientific endeavors, plays a pivotal role in several key applications. Delve into the versatility of L-Lysine-[6-13C,ε-15N] hydrochloride with heightened perplexity and burstiness:
Metabolic Flux Analysis: In the intricate realm of metabolic studies, L-Lysine-[6-13C,ε-15N] hydrochloride emerges as a crucial tool for tracking the intricate carbon and nitrogen fluxes within cellular pathways. By integrating this labeled compound, researchers embark on a journey to unravel the mysteries of biosynthetic and catabolic processes, shedding light on the nuances of energy metabolism and refining industrial fermentation techniques.
Protein Structure Elucidation: Enter the realm of structural biology, where isotopically labeled amino acids like L-Lysine-[6-13C,ε-15N] take center stage in nuclear magnetic resonance (NMR) spectroscopy. These labels, granting heightened resolution in NMR spectra, empower researchers to decipher the three-dimensional intricacies of proteins with unparalleled precision. This application unveils a world of protein dynamics and interactions at the atomic level, enriching our understanding of molecular structures.
Peptide Synthesis Research: Witness the innovative applications of L-Lysine-[6-13C,ε-15N] hydrochloride in the realm of peptide synthesis, where labeled peptides pave the way for exploring protein-protein interactions and molecular folding processes. By incorporating this labeled amino acid into synthetic peptides, researchers embark on a quest to monitor conformational changes and track incorporation dynamics. This journey fuels the exploration of peptide-based therapeutics and novel drug delivery systems, heralding a new era of medical advancements.
Nutrient Assimilation Studies: Journey into the fields of ecological and agricultural sciences, where L-Lysine-[6-13C,ε-15N] hydrochloride stands as a beacon for tracing nitrogen and carbon assimilation in plants and microorganisms. In experiments utilizing labeled nutrients, scientists unravel the efficiency of nutrient uptake and utilization, enriching our understanding of crop nutrition and ecological nutrient cycles. This research serves as a cornerstone for sustainable agricultural practices and ecological balance, fostering a harmonious coexistence with nature.
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