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L-Lysine-[d9] Dihydrochloride

General Information
Catalog: BLP-004336
Molecular Formula: C6H7D9Cl2N2O2
Molecular Weight: 228.17
Chemical Structure
L-Lysine-[d9] Dihydrochloride
Description L-Lysine-[d9] Dihydrochloride is the labelled analogue of L-Lysine Dihydrochloride, which is a naturally occurring amino acid used in the labelling of human bone marrow mesenchymal stem cells for analysis.
Synonyms L-Lysine-D9 Dihydrochloride; (2S)-2,6-diaminohexanoic acid-D9 dihydrochloride; H-Lys-OH-d9 2HCl
Related CAS 657-26-1 (unlabelled)
Purity 98% by CP; 98% atom D

L-Lysine-[d9] dihydrochloride, a stable isotopic variant of the crucial amino acid lysine, finds widespread utility in various scientific and industrial settings. Here are pivotal applications of L-Lysine-[d9] dihydrochloride presented with a high degree of perplexity and burstiness:

Metabolic Tracing: Integral to research endeavors, L-Lysine-[d9] dihydrochloride serves as a tracer in metabolic inquiries, facilitating the monitoring of protein synthesis and breakdown. By integrating this isotopically tagged lysine into proteins, scientists can analyze metabolic fluxes under diverse physiological contexts. This technique proves invaluable, particularly in comprehending conditions like cancer, where protein metabolism undergoes significant alterations.

Mass Spectrometry: For accurate protein quantification and comparison in proteomic analyses, L-Lysine-[d9] dihydrochloride, labeled with stable isotopes, functions as an internal standard in mass spectrometric assessments. Leveraging this compound enhances the precision and dependability of mass spectrometry data, aiding researchers in refining their analytical results across different samples.

Nutritional Studies: In delving into amino acid metabolism, L-Lysine-[d9] dihydrochloride plays a pivotal role in dietary intake investigations involving humans and animals. Through the administration of this labeled amino acid, researchers can explore absorption kinetics, bioavailability, and metabolic pathways. These studies are instrumental in shaping dietary guidelines and advancing therapeutic interventions in the realm of nutrition.

Pharmaceutical Development: Within the pharmaceutical domain, L-Lysine-[d9] dihydrochloride emerges as a valuable asset in the evaluation and enhancement of novel drugs. Its stable isotope tag facilitates rigorous scrutiny of drug metabolism and pharmacokinetics, enabling detailed tracking of drug transformation processes within the body. This aids in dose optimization, refining drug formulations, and augmenting therapeutic efficacy and safety profiles.

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