L-Methionine-[1-13C,15N]

L-Methionine-[1-13C,15N], a specialized labeled amino acid, finds its applications across various research and medical domains. Here are the key applications of L-Methionine-[1-13C,15N]:

Metabolic Flux Analysis: Delving into cellular metabolism, researchers employ L-Methionine-[1-13C,15N] for metabolic flux analysis, tracing metabolic pathways with precision. By integrating this isotopically labeled methionine into cells, scientists unravel the intricate processing of methionine and its derivatives through diverse metabolic routes. This method is indispensable for comprehensively understanding metabolic disorders and optimizing cellular processes for advanced biotechnological applications.

Protein Structural Studies: In the realm of structural biology, L-Methionine-[1-13C,15N] plays a pivotal role in NMR spectroscopy and mass spectrometry for scrutinizing protein structures and dynamics. The distinctive isotopic labeling elevates the resolution of spectroscopic data, enabling scientists to pinpoint specific amino acid residues within complex protein architectures. Such detailed information is paramount for refining drug design strategies and enhancing protein engineering endeavors.

Clinical Diagnostics: Within the realm of medical diagnostics, L-Methionine-[1-13C,15N] emerges as a valuable tool, particularly in PET imaging applications. By tracking this labeled methionine within the body, clinicians can identify and monitor cancerous tumors as heightened methionine uptake is often indicative of rapidly proliferating cells. This innovative application facilitates early detection and precise treatment planning for individuals battling cancer.

Nutritional Research: In the domain of nutritional science, L-Methionine-[1-13C,15N] serves as a key component in exploring amino acid metabolism and its implications for health and disease. Researchers leverage this labeled compound to examine how dietary methionine influences processes like protein synthesis, methylation reactions, and overall nutritional well-being. This knowledge is instrumental in crafting targeted dietary interventions and unraveling the ramifications of amino acid imbalances on human health.