L-Methionine-[2-13C]

L-Methionine-[2-13C], a stable isotope-labeled amino acid utilized in diverse scientific research applications, serves as a cornerstone in various fields. Here are key applications of L-Methionine-[2-13C] presented with a high degree of perplexity and burstiness:

Metabolic Flux Analysis: Delving into the intricate world of cellular metabolism, researchers harness L-Methionine-[2-13C] to engage in metabolic flux analysis, meticulously tracing and quantifying metabolic pathways within living cells. By integrating this labeled methionine into cellular metabolism, scientists can meticulously measure the carbon flow through diverse biochemical pathways. This cutting-edge technique offers profound insights into metabolic regulation and adaptations under varying physiological conditions.

Protein Turnover Studies: Catalysts of breakthroughs in proteomics research, L-Methionine-[2-13C] emerges as a pivotal tool in exploring protein synthesis and degradation rates. The strategic incorporation of the isotope into nascent proteins enables researchers to meticulously track protein turnover, unlocking invaluable insights into the dynamic realm of protein dynamics. This methodology proves particularly instrumental in unraveling disease progression and assessing therapeutic impacts on protein metabolism.

Nutritional Studies: The significance of L-Methionine-[2-13C] extends to nutritional studies, where it plays a pivotal role in evaluating methionine bioavailability and utilization in both human subjects and animals. By administering the labeled methionine, researchers embark on a journey to monitor its absorption, distribution, and integration into various tissues. This wealth of information stands as a cornerstone in exploring dietary requirements and unraveling the intricate role of methionine in the realms of health and disease.

Methylation Research: Delving into the realm of methylation processes, L-Methionine-[2-13C] emerges as a beacon of insight, given methionine's crucial role as a precursor to the universal methyl donor S-adenosylmethionine (SAM). Armed with this potent tool, researchers delve into the study of methylation pattern alterations in DNA, proteins, and other molecular entities. This profound investigation sheds light on epigenetic modifications and their profound implications in the realms of gene regulation and avant-garde cancer research efforts.