Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009072 |
Molecular Formula: C3[13C]2H13ClN2O2 |
Molecular Weight: 170.61 |
Chemical Structure |
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Description | L-Ornithine-[1,2-13C2] hydrochloride is the isotope form of L-Ornithine Hydrochloride, which is a non-essential amino acid for human development but is required intermediate in arginine biosynthesis. |
Synonyms | L-Ornithine hydrochloride 13C2 |
IUPAC Name | (S)-2,5-diaminopentanoic-1,2-13C2 acid hydrochloride |
Related CAS | 3184-13-2 (unlabelled) |
Purity | 98% by CP; 99% atom 13C |
Solubility | Soluble in Methanol, Water |
Appearance | White to Off-white Solid |
Storage | Store at -20°C |
L-Ornithine-[1,2-13C2] hydrochloride emerges as a pivotal compound in tracer studies and metabolic inquiries, boasting widespread utility in various fields. Here are the key applications of L-Ornithine-[1,2-13C2] hydrochloride:
Metabolic Flux Analysis: Delving into the intricate web of metabolic pathways, researchers wield L-Ornithine-[1,2-13C2] hydrochloride to scrutinize the fluxes coursing through organisms. By tracking the journey of labeled carbon atoms, scientists can map out the destiny of ornithine within the urea cycle and its interconnected metabolic highways. This knowledge serves as a beacon, illuminating the depths of metabolic disorders and fueling the optimization of engineering strategies aimed at metabolic mastery.
Nutritional Studies: In the realm of nutritional exploration, this compound stands as a beacon of insight into protein metabolism and amino acid utilization across species. Through dissecting the assimilation of 13C-labeled ornithine into diverse biological tissues, scientists can glean pearls of wisdom regarding nitrogen balance and the intricate dance of protein turnover. This trove of knowledge acts as a compass, guiding the development of tailored dietary interventions and bespoke supplements.
Drug Metabolism Research: Navigating the labyrinth of pharmacokinetics, L-Ornithine-[1,2-13C2] hydrochloride emerges as a potent tool for unraveling the mysteries shrouding ornithine-based drugs or prodrugs. By tracing the footsteps of the labeled compound, researchers embark on a quest to unveil the metabolic pathways, bioavailability nuances, and elimination patterns characterizing these therapeutic agents. This voyage of discovery fuels the formulation of pharmaceutical elixirs that wield effectiveness and safety in equal measure.
Cancer Research: In the realm of oncological exploration, L-Ornithine-[1,2-13C2] hydrochloride emerges as a beacon of hope, offering insights into the metabolic symphony dictating tumor progression and ornithine's enigmatic role in fueling cancer cell proliferation. By tracing the footsteps of labeled ornithine, scientists delve into the metabolic tapestry woven by cancer cells, unearthing potential avenues for therapeutic intervention. This frontier of research kindles the flames of hope for metabolic-centric cancer therapies, paving the way for a brighter tomorrow in the fight against malignancy.
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