L-Ornithine-[d7] hydrochloride - Isotope / BOC Sciences

General Information
Catalog: BLP-009079
Molecular Formula: C5H6D7ClN2O2
Molecular Weight: 175.67

General Information

Catalog: BLP-009079

Molecular Formula: C5H6D7ClN2O2

Molecular Weight: 175.67

Chemical Structure

Description	L-Ornithine-[d7] hydrochloride is the isotope form of L-Ornithine Hydrochloride, which is a non-essential amino acid for human development but is required intermediate in arginine biosynthesis.
Synonyms	L-Ornithine-d7 hydrochloride; H-L-Orn-OH-d7 HCl
IUPAC Name	(S)-2,5-diamino-2,3,3,4,4,5,5-heptadeuteriopentanoic acid;hydrochloride
Related CAS	3184-13-2 (unlabelled)
Canonical SMILES	C(CC(C(=O)O)N)CN.Cl
InChI	InChI=1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/i1D2,2D2,3D2,4D;
InChI Key	GGTYBZJRPHEQDG-HVAXMCRXSA-N
Melting Point	232-234°C
Purity	98% by CP; 98% atom D
Solubility	Soluble in Methanol, Water
Appearance	White to Off-white Solid
Storage	Store at -20°C

L-Ornithine-[d7] hydrochloride is an isotopically labeled compound used in various bioscience research applications. Here are some key applications of L-Ornithine-[d7] hydrochloride:

Metabolic Studies: L-Ornithine-[d7] hydrochloride is essential for tracer studies in metabolic research. It allows scientists to investigate the pathways and rate of ornithine metabolism in cells. This can provide insights into amino acid cycling, urea cycle function, and overall nitrogen metabolism.

Protein Turnover Analysis: In proteomics, L-Ornithine-[d7] hydrochloride is used to study protein turnover rates. By incorporating this isotopically labeled compound into cellular proteins, researchers can track and quantify the synthesis and degradation of proteins over time. This is crucial for understanding cellular dynamics and protein homeostasis.

Pharmacokinetics: L-Ornithine-[d7] hydrochloride can be employed to study the pharmacokinetics of drugs that interact with the urea cycle. By monitoring its distribution, absorption, and excretion, researchers can elucidate how drugs affect metabolic pathways involving ornithine. This information is vital for the development of therapeutic agents targeting metabolic disorders.

Nutritional Research: This isotopically labeled compound is used to trace the in vivo utilization of dietary ornithine. Studies involving L-Ornithine-[d7] hydrochloride help in understanding how different diets influence nitrogen balance and amino acid utilization. This can aid in designing nutritional interventions for conditions such as growth deficiencies or metabolic imbalances.