Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009079 |
Molecular Formula: C5H6D7ClN2O2 |
Molecular Weight: 175.67 |
Chemical Structure |
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Description | L-Ornithine-[d7] hydrochloride is the isotope form of L-Ornithine Hydrochloride, which is a non-essential amino acid for human development but is required intermediate in arginine biosynthesis. |
Synonyms | L-Ornithine-d7 hydrochloride; H-L-Orn-OH-d7 HCl |
IUPAC Name | (S)-2,5-diamino-2,3,3,4,4,5,5-heptadeuteriopentanoic acid;hydrochloride |
Related CAS | 3184-13-2 (unlabelled) |
Canonical SMILES | C(CC(C(=O)O)N)CN.Cl |
InChI | InChI=1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/i1D2,2D2,3D2,4D; |
InChI Key | GGTYBZJRPHEQDG-HVAXMCRXSA-N |
Melting Point | 232-234°C |
Purity | 98% by CP; 98% atom D |
Solubility | Soluble in Methanol, Water |
Appearance | White to Off-white Solid |
Storage | Store at -20°C |
L-Ornithine-[d7] hydrochloride is an isotopically labeled compound used in various bioscience research applications. Here are some key applications of L-Ornithine-[d7] hydrochloride:
Metabolic Studies: L-Ornithine-[d7] hydrochloride is essential for tracer studies in metabolic research. It allows scientists to investigate the pathways and rate of ornithine metabolism in cells. This can provide insights into amino acid cycling, urea cycle function, and overall nitrogen metabolism.
Protein Turnover Analysis: In proteomics, L-Ornithine-[d7] hydrochloride is used to study protein turnover rates. By incorporating this isotopically labeled compound into cellular proteins, researchers can track and quantify the synthesis and degradation of proteins over time. This is crucial for understanding cellular dynamics and protein homeostasis.
Pharmacokinetics: L-Ornithine-[d7] hydrochloride can be employed to study the pharmacokinetics of drugs that interact with the urea cycle. By monitoring its distribution, absorption, and excretion, researchers can elucidate how drugs affect metabolic pathways involving ornithine. This information is vital for the development of therapeutic agents targeting metabolic disorders.
Nutritional Research: This isotopically labeled compound is used to trace the in vivo utilization of dietary ornithine. Studies involving L-Ornithine-[d7] hydrochloride help in understanding how different diets influence nitrogen balance and amino acid utilization. This can aid in designing nutritional interventions for conditions such as growth deficiencies or metabolic imbalances.
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