L-Ornithine-[alpha-15N] hydrochloride

L-Ornithine-[alpha-15N] hydrochloride, a stable isotope-labeled compound widely utilized in metabolic research and diverse bioscience applications, offers intricate possibilities. Here are the key applications of L-Ornithine-[alpha-15N] hydrochloride:

Metabolic Tracing: Delving into metabolic pathways, particularly in amino acid metabolism and the urea cycle, this labeled compound is a valuable tool. By integrating L-Ornithine-[alpha-15N] into biological systems, researchers can meticulously track the incorporation and transformation of nitrogen within complex metabolic networks, shedding light on fluxes and regulatory mechanisms in nitrogen metabolism.

Nutritional Biochemistry: In nutritional studies, L-Ornithine-[alpha-15N] hydrochloride plays a pivotal role in unraveling protein and amino acid metabolism intricacies. Utilizing isotopic labeling, researchers can quantitatively measure nitrogen retention and utilization in tissues, offering insights into protein synthesis, degradation, and overall nitrogen balance. This knowledge is invaluable for optimizing dietary formulations and elucidating metabolic disorders, contributing to a deeper understanding of nutritional science.

Cell Culture Studies: Within the realm of cell biology, this isotope-labeled compound serves as a powerful tool for investigating the impacts of L-ornithine on cell growth, proliferation, and differentiation. By introducing L-Ornithine-[alpha-15N] into cell culture media, researchers can monitor the uptake and utilization of this amino acid across various cell types. These studies advance our understanding of tissue engineering, regenerative medicine, and cancer research, unveiling new possibilities in cellular studies.

Pharmacokinetics: In pharmacokinetic assessments, L-Ornithine-[alpha-15N] hydrochloride emerges as a critical element for analyzing the absorption, distribution, metabolism, and excretion (ADME) of drugs related to L-ornithine metabolism. The nitrogen label provides precise tracking and quantification in biological samples, furnishing essential data for comprehending drug interactions and optimizing therapeutic strategies, propelling pharmaceutical research into new frontiers of precision medicine.