L-Phenylalanine [Ring-13C6]

L-Phenylalanine [Ring-13C6], a stable isotope-labeled compound extensively utilized in bioscience research, offers diverse applications. Here are the key applications of L-Phenylalanine [Ring-13C6]:

Metabolic Flux Analysis: Employing L-Phenylalanine [Ring-13C6] for metabolic flux analysis illuminates the journey of phenylalanine through intricate metabolic pathways. By tracing the labeled carbon atoms, researchers unveil insights into amino acid metabolism and pinpoint regulatory hotspots critical for comprehending metabolic disorders and fine-tuning metabolic engineering strategies.

Protein Structure and Function Studies: Within the realm of protein biochemistry, the incorporation of L-Phenylalanine [Ring-13C6] into proteins unlocks a treasure trove of knowledge about their structure, dynamics, and interactions. Mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy serve as trusty companions in dissecting these labeled proteins, offering a profound understanding of protein folding, stability, and function.

Pharmacokinetics and Drug Development: Unraveling the mysteries of pharmacokinetics, the labeled version of phenylalanine is a linchpin in tracking the journey of drugs through absorption, distribution, metabolism, and excretion pathways. Integrating L-Phenylalanine [Ring-13C6] into drug candidates enables researchers to monitor their metabolic fate and behavior within the body, facilitating the development of potent and safer pharmaceutical agents.

Nutritional Studies: In the realm of nutritional science, L-Phenylalanine [Ring-13C6] acts as a beacon for exploring the metabolism of phenylalanine under various dietary scenarios. This exploration sheds light on the role of this amino acid in growth, development, and overall well-being. Furthermore, it serves as a key tool in investigating phenylalanine metabolism in individuals grappling with metabolic disorders like phenylketonuria (PKU), offering insights into personalized nutrition interventions.