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L-Selenomethionine-[methyl-13C]

General Information
Catalog: BLP-009833
CAS: 1217470-45-5
Molecular Formula: C4[13C]H11NO2Se
Molecular Weight: 197.1
Chemical Structure
L-Selenomethionine-[methyl-13C]
Description L-Selenomethionine-[methyl-13C] is a labelled L-Selenomethionine. Selenomethionine is composed of the amino acid methionine and selenium.
IUPAC Name (2S)-2-amino-4-(1-13C)methylselanylbutanoic acid
Related CAS 3211-76-5 (unlabelled)
Isomeric SMILES [13CH3][Se]CC[C@@H](C(=O)O)N
Canonical SMILES C[Se]CCC(C(=O)O)N
InChI InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1/i1+1
InChI Key RJFAYQIBOAGBLC-YWQIHCTDSA-N
Melting Point 265-267°C(lit.)
Purity 95% by HPLC; 99% atom 13C

L-Selenomethionine-[methyl-13C] is a labeled amino acid compound used in various scientific and research applications. Here are some key applications of L-Selenomethionine-[methyl-13C]:

Nutritional and Metabolic Studies: L-Selenomethionine-[methyl-13C] is instrumental in studying selenium metabolism and utilization in the human body. By tracing the labeled compound in metabolic pathways, researchers can better understand the role of selenium in nutrition and its impact on health. This knowledge is crucial for developing dietary recommendations and understanding selenium-related diseases.

Protein Structure Analysis: This labeled compound is used in nuclear magnetic resonance (NMR) spectroscopy to study the structure and dynamics of proteins. Incorporating L-Selenomethionine-[methyl-13C] into proteins allows scientists to gain detailed insights into protein folding, interactions, and conformational changes. These studies are vital for drug design and understanding protein function at the molecular level.

Antioxidant Research: L-Selenomethionine-[methyl-13C] is utilized to investigate the antioxidant properties of selenium and its derivatives. Researchers can explore how selenium protects cells from oxidative stress and its potential role in preventing diseases associated with oxidative damage. This knowledge contributes to the development of selenium-based antioxidant therapies and supplements.

Cancer Research: In cancer biology, L-Selenomethionine-[methyl-13C] serves as a tool for studying the pathways influenced by selenium in cancer cells. Researchers can track its incorporation into selenoproteins and analyze the effects on tumor growth and progression. This application aids in uncovering potential therapeutic strategies that leverage selenium’s properties in cancer prevention and treatment.

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