Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-009886 |
CAS: 95034-57-4 |
Molecular Formula: C3H5D2NO3 |
Molecular Weight: 107.10 |
Chemical Structure |
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Catalog Number | Size | Price | Stock | Quantity |
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BLP-009886 | 100 mg | $899 | In stock |
Description | L-Serine-[3,3-d2] is a labelled L-Serine. Serine is an α-amino acid used in the biosynthesis of proteins. |
Synonyms | L-Serine-d2 |
IUPAC Name | (2S)-2-amino-3,3-dideuterio-3-hydroxypropanoic acid |
Related CAS | 56-45-1 (unlabelled) |
Canonical SMILES | C(C(C(=O)O)N)O |
InChI | InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1/i1D2 |
InChI Key | MTCFGRXMJLQNBG-XFJCSJJYSA-N |
Purity | 98% by HPLC; 98% atom D |
L-Serine-[3,3-d2], a deuterium-labeled amino acid utilized in diverse scientific and industrial settings, presents a myriad of applications. Here are the key applications of L-Serine-[3,3-d2]:
Metabolic Flux Analysis: Embedded in the realm of metabolic flux analysis is the utility of L-Serine-[3,3-d2]. This labeled amino acid serves as a tracing tool, illuminating pathways that involve serine within cellular systems. By tracking its conversion into other metabolites, researchers gain pivotal insights into the intricate web of metabolic networks and the multifaceted roles played by serine in cellular physiology.
Proteomics: Unveiling a distinctive facet of its utility, L-Serine-[3,3-d2] finds its application in the realm of proteomics. Through its incorporation into proteins during synthesis, scientists can pinpoint and quantify proteins leveraging mass spectrometry. This labeling aids in discerning between freshly synthesized proteins and those existing beforehand, ultimately contributing to a deeper comprehension of protein dynamics, turnover, and post-translational modifications.
Neuroscience Research: Delving into the sphere of neuroscience research, L-Serine-[3,3-d2] emerges as a pivotal player in unraveling the enigmatic role of serine in neurotransmission and brain metabolism. This exploration opens doorways to understanding neurodegenerative diseases and identifying potential therapeutic targets.
Pharmaceutical Development: Spearheading advancements in the pharmaceutical domain, L-Serine-[3,3-d2] stands as a valuable asset for crafting new drugs. Through its integration into drug metabolism studies, researchers gain deeper insights into how drugs intersect with metabolic pathways involving serine. This knowledge forms the bedrock for refining drug design, enhancing efficacy, and ensuring safety in pharmaceutical development.
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