L-Threonine-[4-13C,2,3-d2]

L-Threonine-[4-13C,2,3-d2], a labeled amino acid utilized in advanced research, finds diverse applications in cutting-edge studies. Explore the key applications of L-Threonine-[4-13C,2,3-d2]:

Metabolic Flux Analysis: Delving into metabolic pathways and metabolite flow within cells, scientists leverage L-Threonine-[4-13C,2,3-d2] for intricate metabolic flux analysis. By tracing the incorporation of labeled carbon and deuterium atoms, researchers unravel the dynamics of amino acid metabolism, offering profound insights into cellular metabolic states and perturbations.

Protein Structure and Dynamics: At the forefront of protein research, L-Threonine-[4-13C,2,3-d2] plays a pivotal role in nuclear magnetic resonance (NMR) spectroscopy studies to explore protein structure and dynamics. The integration of the labeled amino acid into proteins facilitates the elucidation of conformational changes and atomic-level interactions, crucial for deciphering protein function and designing innovative therapeutics.

Stable Isotope-Resolved Metabolomics: In the realm of stable isotope-resolved metabolomics, L-Threonine-[4-13C,2,3-d2] emerges as a cornerstone for analyzing metabolic alterations under different conditions or treatments. This labeled compound aids in tracing specific metabolic pathways and detecting shifts in metabolite pools, offering invaluable insights into disease metabolism, drug responses, and cellular adaptations to environmental challenges.

Nutritional Research: In the domain of nutritional investigations, L-Threonine-[4-13C,2,3-d2] serves as a valuable tool to probe amino acid absorption, assimilation, and nitrogen metabolism in organisms. By monitoring the distribution of the labeled amino acid, researchers gain deeper insights into nutrient utilization and dietary requirements, vital for optimizing nutritional strategies and crafting fortified diets.