L-Tyrosine-[phenol-3,5-13C2]

L-Tyrosine-[phenol-3,5-13C2], a stable isotopically labeled amino acid, finds diverse applications in scientific research. Here are the key applications of L-Tyrosine-[phenol-3,5-13C2]:

Metabolic Flux Analysis: Playing a pivotal role in metabolic flux analysis, L-Tyrosine-[phenol-3,5-13C2] serves as a tool for tracing and quantifying metabolic pathways within cells. By integrating the labeled tyrosine into cellular metabolism, researchers can meticulously monitor the flow of carbon through intricate biochemical networks. This innovative approach offers invaluable insights into cellular metabolism dynamics and aids in optimizing industrial fermentation processes with precision.

Protein Structure and Dynamics Studies: Embraced by structural biologists, L-Tyrosine-[phenol-3,5-13C2] takes center stage in nuclear magnetic resonance (NMR) spectroscopy for unraveling the intricacies of protein structure and dynamics. The carbon-13 label enables an in-depth exploration of tyrosine residues within proteins, unveiling crucial details about protein folding, interactions, and conformational changes. This application stands as a critical cornerstone for unraveling protein functions and paving the way for the development of cutting-edge therapeutic strategies.

Neurotransmitter Research: Delving into the realms of neuroscience, L-Tyrosine-[phenol-3,5-13C2] emerges as a key player in unraveling the mysteries of tyrosine metabolism and its conversion into neurotransmitters like dopamine and norepinephrine. By monitoring the labeled tyrosine, scientists are able to probe the intricacies of neurotransmitter synthesis and release mechanisms within neuronal systems. This groundbreaking research contributes significantly to our comprehension of neurological disorders and the formulation of innovative treatment approaches, pushing the boundaries of neuroscientific discovery.

Pharmacokinetic Studies: In the arena of pharmacokinetics, L-Tyrosine-[phenol-3,5-13C2] takes on a crucial role in studying the absorption, distribution, metabolism, and excretion of tyrosine-based pharmaceuticals. The isotopic label offers a precise means of measuring drug kinetics within biological systems, providing invaluable data for enhancing drug formulations and boosting therapeutic efficacy to new heights. This application stands as a cornerstone for advancing pharmacological research and revolutionizing drug development practices.