MAM2201 4-Hydroxypentyl metabolite-[d5] (indole-[d5])

MAM2201 4-Hydroxypentyl metabolite-[d5] (indole-[d5]) is a labeled metabolite used in various research fields. Here are some key applications of this compound:

Pharmacokinetics Studies: The use of MAM2201 4-Hydroxypentyl metabolite-[d5] is critical in pharmacokinetics to understand how synthetic cannabinoids are metabolized in the body. By tracking the labeled metabolite, researchers can determine the absorption, distribution, metabolism, and excretion (ADME) profiles of the parent compound. This information is essential for drug development and regulatory assessments.

Toxicological Research: MAM2201 4-Hydroxypentyl metabolite-[d5] serves as a reference standard in toxicological studies to investigate the effects of synthetic cannabinoids on biological systems. By comparing the metabolic pathways and toxicological profiles of labeled and unlabeled metabolites, researchers can better assess the risks and safety of these substances. This aids in the formulation of guidelines for their use and control.

Clinical and Forensic Testing: In forensic and clinical toxicology, MAM2201 4-Hydroxypentyl metabolite-[d5] is used as an internal standard for the detection and quantification of synthetic cannabinoids in biological samples. Its presence helps ensure accuracy and reliability in analytical methods such as mass spectrometry. This application is crucial for drug testing, legal investigations, and monitoring substance abuse.

Method Development and Validation: Researchers use MAM2201 4-Hydroxypentyl metabolite-[d5] to develop and validate new analytical methodologies for detecting synthetic cannabinoids and their metabolites. By incorporating the labeled compound into test protocols, scientists can optimize assay sensitivity, specificity, and reproducibility. This ensures robust and reliable analytical procedures for both research and diagnostic purposes.