Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
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Catalog: BLP-004881 |
CAS: 1217046-73-5 |
Molecular Formula: C14H8D5NO |
Molecular Weight: 216.29 |
Chemical Structure |
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Synonyms | N-Acetyl-4-aminobiphenyl D5; N-[1,1'-Biphenyl-d5]-4-ylacetamide; 4-(Acetylamino)biphenyl-d5; 4'-Phenylacetanilide-d5; NSC 227192-d5; p-Phenylacetanilide-d5 |
IUPAC Name | N-[4-(2,3,4,5,6-pentadeuteriophenyl)phenyl]acetamide |
Related CAS | 4075-79-0 (unlabelled) |
Canonical SMILES | CC(=O)NC1=CC=C(C=C1)C2=CC=CC=C2 |
InChI | InChI=1S/C14H13NO/c1-11(16)15-14-9-7-13(8-10-14)12-5-3-2-4-6-12/h2-10H,1H3,(H,15,16)/i2D,3D,4D,5D,6D |
InChI Key | SVLDILRDQOVJED-VIQYUKPQSA-N |
Melting Point | 171-173°C |
Solubility | Soluble in DMSO, Methanol |
Appearance | Off-white Solid |
Storage | Store at 2-8°C |
N-Acetyl-4-aminobiphenyl-[d5] is a stable isotope-labeled compound used in scientific research for various applications. Here are some key applications of N-Acetyl-4-aminobiphenyl-[d5]:
Pharmacokinetics Studies: N-Acetyl-4-aminobiphenyl-[d5] is employed in pharmacokinetic studies to understand the absorption, distribution, metabolism, and excretion of therapeutic compounds. By using this labeled compound, researchers can trace the metabolic pathways and interactions of drugs within biological systems. This data is crucial for optimizing dosage regimens and ensuring drug safety and efficacy.
Metabolomics: In metabolomics, N-Acetyl-4-aminobiphenyl-[d5] serves as an internal standard for accurate quantification of metabolites in complex biological samples. Its stable isotope labeling facilitates precise mass spectrometric analysis, allowing for the assessment of metabolic profiles. This aids in the identification of biomarkers and understanding metabolic dynamics in health and disease.
Environmental Monitoring: N-Acetyl-4-aminobiphenyl-[d5] can be used in environmental studies to trace the fate and transport of pollutants. Its distinct isotopic signature allows researchers to track its behavior in ecosystems and evaluate pollutant degradation processes. This knowledge assists in developing strategies for pollution control and risk assessment.
Chemical Reaction Mechanism Studies: In mechanistic chemistry research, N-Acetyl-4-aminobiphenyl-[d5] is used to investigate reaction pathways and mechanisms. Utilizing this labeled compound helps scientists discern between different potential reaction routes by analyzing isotopic distribution in products. Such insights are valuable for designing more efficient catalytic processes and advancing synthetic chemistry techniques.
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