N-Acetyl-L-serine-[2,3,3-d3] - Isotope / BOC Sciences

General Information
Catalog: BLP-009522
Molecular Formula: C5H6D3NO4
Molecular Weight: 150.15

General Information

Catalog: BLP-009522

Molecular Formula: C5H6D3NO4

Molecular Weight: 150.15

Chemical Structure

Description	N-Acetyl-L-serine-[2,3,3-d3] is a deuterium analogue of N-Acetyl-L-serine. N-Acetyl-L-serine is useful for studying wheat drought tolerance.
Synonyms	Ac-L-Se-OH-d3; N-Acetyl-L-serine-2,3,3-d3; (2S)-2-acetamido-3-hydroxy(D3)propanoic acid
Related CAS	16354-58-8 (unlabelled)
InChI	InChI=1S/C5H9NO4/c1-3(8)6-4(2-7)5(9)10/h4,7H,2H2,1H3,(H,6,8)(H,9,10)/t4-/m0/s1/i2D2,4D
InChI Key	JJIHLJJYMXLCOY-BWBLNMPZSA-N
Purity	98% by CP; 98% atom D
Appearance	White Solid

N-Acetyl-L-serine-[2,3,3-d3], a deuterated amino acid with diverse bioscience applications, is a key component in various scientific endeavors. Here are the crucial applications of N-Acetyl-L-serine-[2,3,3-d3]:

Metabolomics: Acting as an internal standard in mass spectrometry-based metabolomic research, N-Acetyl-L-serine-[2,3,3-d3] stands out for its deuterated form, facilitating precise quantification and identification of serine and its derivatives within intricate biological samples. This enables a comprehensive understanding of metabolic pathways and the nuanced changes in diverse physiological and pathological conditions.

Protein Research: In the realm of protein structure and function studies, the significance of this deuterated amino acid shines through, particularly in nuclear magnetic resonance (NMR) spectroscopy. By integrating N-Acetyl-L-serine-[2,3,3-d3] into proteins, scientists unlock detailed insights into protein dynamics and the nuanced conformational shifts, contributing to a profound comprehension of protein behavior and molecular-level interactions.

Isotope Tracing: The strategic application of N-Acetyl-L-serine-[2,3,3-d3] in isotope tracing experiments unveils the intricate metabolic fluxes and pathways within biological systems. By meticulously monitoring the incorporation and transformation of deuterated serine, researchers illuminate the dynamic flow of metabolites, uncovering novel metabolic routes crucial for metabolic engineering and innovative therapeutic interventions.

Pharmaceutical Development: Within the realm of drug development, N-Acetyl-L-serine-[2,3,3-d3] emerges as a pivotal tool for unraveling drug metabolism and pharmacokinetics. The stable isotope labeling inherent in this compound aids in tracing the distribution and breakdown of drugs in the body, providing indispensable insights for dosage optimization and efficacy assessments. This strategic application ensures the development of safer and more potent therapeutic agents, driving forward the frontier of pharmaceutical science.