Nε-(Ethoxycarbonylmethyl)-L-lysine Methyl Ester-[d4]

Nε-(Ethoxycarbonylmethyl)-L-lysine Methyl Ester-[d4] is a chemical compound with several unique applications in research and development. Here are some key applications of this compound:

Isotope-Labeled Tracers: This deuterated compound can be used as an isotope-labeled tracer in metabolic studies, allowing researchers to track the incorporation and metabolism of lysine in biological systems. By monitoring the deuterium label, scientists can gain insights into protein turnover and amino acid metabolism. This aids in understanding metabolic dynamics in health and disease.

Proteomics Research: In proteomics, Nε-(Ethoxycarbonylmethyl)-L-lysine Methyl Ester-[d4] can be used to study post-translational modifications of proteins. The isotope labeling helps identify and quantify modifications such as methylation and acetylation. This is crucial for unraveling protein function and the regulation of complex cellular processes.

Drug Metabolism Studies: This compound serves as a valuable tool in drug metabolism research to study lysine modifications in drug-protein adducts. By using the deuterated form, researchers can enhance the sensitivity and specificity of mass spectrometric analyses. This information is vital for assessing the safety and efficacy of pharmaceutical compounds.

Analytical Chemistry: In the field of analytical chemistry, Nε-(Ethoxycarbonylmethyl)-L-lysine Methyl Ester-[d4] can be utilized as an internal standard for quantifying related compounds in complex mixtures. Its distinct isotopic signature helps in differentiating between analytes and improving accuracy in quantification. This application is integral to ensuring precise and reliable analytical results.