N-(Phenylacetyl-[d5])glycine

N-(Phenylacetyl-[d5])glycine, a deuterium-labeled compound widely utilized in research and analytical chemistry, has diverse applications. Here are the key applications:

Mass Spectrometry: A cornerstone in mass spectrometry, N-(Phenylacetyl-[d5])glycine serves as a crucial internal standard for quantifying glycine and related metabolites. The deuterium label enables precise differentiation from endogenous compounds, ensuring meticulous and reproducible analytical outcomes. This is particularly vital for studies delving into metabolic profiling and uncovering biomarkers essential for scientific progress.

Pharmacokinetics: In the realm of drug development, N-(Phenylacetyl-[d5])glycine emerges as a potent tool for tracing and comprehending the pharmacokinetics of glycine-associated medications. By integrating the deuterium-labeled compound, researchers can meticulously measure absorption, distribution, metabolism, and excretion (ADME) parameters, aiding in the refinement of drug formulations and dosing strategies crucial for effective therapeutic interventions.

Stable Isotope Labeling: Playing a pivotal role in stable isotope labeling experiments, N-(Phenylacetyl-[d5])glycine facilitates the tracing of metabolic pathways and fluxes within biological systems. The deuterium label acts as a safe and efficient non-radioactive tracer, ideal for prolonged investigative endeavors. Utilizing this methodology, researchers can glean profound insights into the intricate metabolic processes and interactions unfolding within cells and organisms, advancing our understanding of biological complexities.

Structural Analysis: Embracing the frontiers of structural biology and chemistry, N-(Phenylacetyl-[d5])glycine empowers scientists to explore the interactions and binding properties of glycine derivatives with unmatched precision. Through the utilization of this compound, researchers can engage in high-resolution nuclear magnetic resonance (NMR) and employ other spectroscopic techniques, shedding light on the molecular architecture and dynamics of biologically relevant molecules. This endeavor enhances our comprehension of the intricate molecular world, propelling scientific discoveries to new heights.