Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
---|
Catalog: BLP-012522 |
CAS: 1329799-64-5 |
Molecular Formula: C6H2D8N2O2 |
Molecular Weight: 150.21 |
Chemical Structure |
---|
![]() |
Description | Piracetam-[d8] is the labelled analogue of Piracetam. Piracetam can be used mainly for myoclonus in UK. |
Synonyms | Piracetam D8; 2-Oxo-1-pyrrolidineacetamide-d8; (2-Oxopyrrolidino)acetamide-d8; 2-(2-Oxopyrrolidin-1-yl)acetamide-d8; Avigilen-d8 |
IUPAC Name | 2,2-dideuterio-2-(2,2,3,3,4,4-hexadeuterio-5-oxopyrrolidin-1-yl)acetamide |
Related CAS | 7491-74-9 (unlabelled) |
Canonical SMILES | C1CC(=O)N(C1)CC(=O)N |
InChI | InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)/i1D2,2D2,3D2,4D2 |
InChI Key | GMZVRMREEHBGGF-SVYQBANQSA-N |
Melting Point | 137-140°C |
Purity | 98% by HPLC; 99% atom D |
Solubility | Soluble in DMSO, Methanol |
Appearance | White to Off-white Solid |
Storage | Store at -20°C |
Piracetam-[d8], a deuterated variant of Piracetam known for its potent cognitive enhancement properties, offers a sophisticated tool for both cognitive enhancement and neurological exploration. Here are the key applications of Piracetam-[d8]:
Pharmacokinetic Studies: By employing Piracetam-[d8] in pharmacokinetic investigations, researchers can meticulously track the drug's absorption, distribution, metabolism, and excretion pathways within the body. The deuterium labeling provides a distinct separation between the administered drug and endogenous metabolites, offering researchers precise insights into how the drug interacts within the complex systems of the body.
Neuropharmacology Research: In the expansive field of neuropharmacology, Piracetam-[d8] emerges as a pivotal tool for unraveling the intricate mechanisms through which nootropic drugs influence cognitive functions and neurological pathways. The stable isotope labeling enables researchers to isolate the specific effects of Piracetam from naturally occurring brain substances, leading to a profound understanding of how Piracetam enhances cognitive performance and modulates brain activities in a nuanced and profound manner.
Biotransformation Studies: Delving into biotransformation studies, the utilization of Piracetam-[d8] sheds light on the metabolic pathways and transformation products of Piracetam. By tracing the deuterated form, researchers can pinpoint the enzymes and metabolic routes involved in drug metabolism, providing essential insights for refining dosing regimens and mitigating potential side effects in a comprehensive and detailed manner.
Drug Interaction Research: Within the realm of drug interaction analysis, Piracetam-[d8] emerges as a key player in elucidating the complexities of how Piracetam interacts with other medications. By harnessing the labeled compound, scientists can explore these interactions without the interference of naturally occurring metabolites, enabling the identification of potential adverse interactions and ensuring the safety and efficacy of combined drug therapies with a meticulous and thorough approach.
Interested in our Service & Products?
Need detailed information?