Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
In addition to treating various diseases, isotopes are used for imaging, diagnosis, and newborn screening.
Small molecule compounds labeled with stable isotopes can be used as chemical reference for chemical identification, qualitative, quantitative, detection, etc. Various types of NMR solvents can be used to study the structure, reaction mechanism and reaction kinetics of compounds.
Stable isotope labeling allows researchers to study metabolic pathways in vivo in a safe manner.
Stable isotope-labeled compounds are used as environmental pollutant standards for the detection of air, water, soil, sediment and food.
General Information |
---|
Catalog: BLP-004472 |
Molecular Formula: C13H17D4ClN2O2 |
Molecular Weight: 276.8 |
Chemical Structure |
---|
![]() |
Description | An isotope labelled derivative of Procaine. Procaine is a local anesthetic drug and can be used to reduce the pain of intramuscular injection of penicillin. |
Synonyms | Procaine D4 Hydrochloride |
IUPAC Name | [1,1,2,2-tetradeuterio-2-(diethylamino)ethyl] 4-aminobenzoate;hydrochloride |
Related CAS | 51-05-8 (unlabelled) |
Canonical SMILES | CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl |
InChI | InChI=1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H/i9D2,10D2; |
InChI Key | HCBIBCJNVBAKAB-PQDNHERISA-N |
Purity | 95% by CP; 99% atom D |
Storage | Store at-20°C |
Procaine-[d4] Hydrochloride, a deuterated variant of Procaine, finds predominant use in research and pharmaceutical realms. Here are the key applications of Procaine-[d4] Hydrochloride:
Pharmacokinetic Studies: Serving as a linchpin in pharmacokinetic explorations, Procaine-[d4] Hydrochloride plays a pivotal role in elucidating the absorption, distribution, metabolism, and excretion of Procaine. The deuterium labeling technique enables precise tracking within biological systems, facilitating meticulous examination through mass spectrometry. By unraveling the drug's behavior within the body, researchers ensure optimal dosing strategies and efficacy outcomes for improved patient care.
Metabolism Research: In the intricate realm of drug metabolism investigations, Procaine-[d4] Hydrochloride emerges as a potent tool for delving into metabolic pathways. Through the strategic substitution of hydrogen atoms with deuterium, researchers distinguish between parent compounds and metabolites amidst complex biological matrices. This distinction aids in identifying metabolic by-products, offering insights into metabolic rates and pathways, thereby advancing our comprehension of drug metabolism intricacies.
Analytical Chemistry: Positioned as a cornerstone in analytical chemistry, Procaine-[d4] Hydrochloride serves as a reliable internal standard, particularly in mass spectrometry-based quantification endeavors. The isotope-labeled compound guarantees precise and dependable measurements of Procaine across diverse sample types such as plasma or tissue extracts. This precision is indispensable for validating analytical methodologies and ensuring research reproducibility, underpinning the foundation of robust scientific inquiry.
Drug Interaction Studies: Within the domain of drug interaction exploration, Procaine-[d4] Hydrochloride emerges as a pivotal player in dissecting the interplay between Procaine and other medications. By monitoring the pharmacokinetic alterations in the presence of concomitant drugs, researchers uncover potential drug-drug interactions and their ramifications. This critical information forms the cornerstone for crafting safe and efficacious polypharmacy regimens, safeguarding patient well-being in the complex landscape of drug interactions.
Interested in our Service & Products?
Need detailed information?