Name: Pyridoxal-[d3] Hydrochloride
Brand: BOC Sciences
Rating: 5 (1 reviews)

General Information

Catalog: BLP-012697

Molecular Formula: C8H7D3ClNO3

Molecular Weight: 206.64

Chemical Structure

Description	Pyridoxal-[d3] Hydrochloride is a labelled analogue of Pyridoxal, which is one of the three natural forms of vitamin B6, the another two are pyridoxamine and pyridoxine.
Synonyms	Pyridoxal-[2H3] hydrochloride
IUPAC Name	3-hydroxy-5-(hydroxymethyl)-2-(trideuteriomethyl)pyridine-4-carbaldehyde;hydrochloride
Related CAS	65-22-5 (unlabelled)
Canonical SMILES	CC1=NC=C(C(=C1O)C=O)CO.Cl
InChI	InChI=1S/C8H9NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,4,10,12H,3H2,1H3;1H/i1D3;
InChI Key	FCHXJFJNDJXENQ-NIIDSAIPSA-N
Melting Point	>150°C (dec.)
Solubility	Soluble in DMSO (Slightly), Methanol (Slightly)
Appearance	Pale Yellow to Light Yellow Solid
Storage	Store at -20°C

Pyridoxal-[d3] Hydrochloride, a stable isotope-labeled compound essential in scientific research, finds diverse applications. Here are the applications:

Metabolic Studies: Widely utilized in metabolic research, Pyridoxal-[d3] Hydrochloride plays a pivotal role in tracing vitamin B6 metabolism within biochemical pathways. By integrating this labeled compound into metabolic tracers, scientists can meticulously monitor vitamin B6 utilization and its conversion into active coenzymes. This meticulous approach is crucial for unraveling the intricate mechanisms of vitamin B6 in both health and disease scenarios.

Nutritional Biochemistry: In the domain of nutritional biochemistry, Pyridoxal-[d3] Hydrochloride is a key tool for investigating the absorption, distribution, and excretion of vitamin B6 in human and animal models. Administering this isotope-labeled compound allows researchers to precisely quantify the bioavailability of dietary vitamin B6. This data aids in crafting comprehensive nutritional recommendations and evaluating the effects of vitamin B6 deficiency or supplementation with a meticulous approach.

Biochemical Assays: Serving as a valuable internal standard in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) assays, Pyridoxal-[d3] Hydrochloride ensures accurate quantification of vitamin B6 forms in biological samples. The labeled compound plays a critical role in guaranteeing precise and reliable measurement of pyridoxal phosphate levels in clinical and research settings, enabling researchers to delve into intricate biochemical processes with meticulous accuracy.

Pharmacokinetics: In pharmacokinetic research, Pyridoxal-[d3] Hydrochloride is a key component in studying the metabolic pathways of vitamin B6 and its analogs. By meticulously tracking the labeled compound in blood, urine, and tissues, researchers can discern essential pharmacokinetic parameters such as absorption rate, half-life, and clearance with a precise approach. This information is indispensable for the development of vitamin B6-based therapeutic agents and understanding their pharmacological profiles with a meticulous and detailed analysis.